In mammals the cell-autonomous circadian clock pivots around a transcriptional/post-translational feedback loop. However, we remain largely ignorant of the critical molecular, cell biological, and circuit-level processes that determine the precision and robustness of circadian rhythms: what keeps them on track, and what determines their period, which varies by less than 5 minutes over 24 hours? The origin of this precision and robustness is the suprachiasmatic nucleus (SCN) of the basal hypothalamus, the principal circadian pacemaker of the brain. The SCN sits atop a circadian hierarchy that sustains and synchronises the innumerable cell-autonomous clocks of all major organs to solar time (and thereby to each other), by virtue of direct retinal innervation that entrains the transcriptional oscillator of the 20,000 or so component cells of the SCN. I shall describe real-time imaging approaches to monitor circadian cycles of gene expression and cellular function in the SCN, and intersectional genetic and pharmacological explorations of the cell-autonomous and circuit-level mechanisms of circadian timekeeping. A particular focus will be on “translational switching” approaches to controlling clock function and the surprising discovery of a central role for SCN astrocytes in controlling circadian behaviour.

Join us at Teddy Hall next week for a fantastic event on the ‘Neuroscience of Dance’ brought to you by the Centre for the Creative Brain!

Science, dance and wine – what more could you want for a Saturday afternoon?

A few (free) tickets are still available, so be quick!

https://www.seh.ox.ac.uk/discover/research/centre-for-the-creative-brain

Automation, AI and robotics are changing our lives quickly – but digital disruption goes much further than we realise.

In this talk, Richard Baldwin, one of the world’s leading globalisation experts, will explain that exponential growth in computing, transmission and storage capacities is also creating a new form of ‘virtual’ globalisation that could undermine the foundations of middle-class prosperity in the West.

This book talk will be followed by a drinks reception and book signing, all welcome.

In 2013, Carl Frey and Michael Osborne published a paper titled ‘The Future of Employment: How Susceptible Are Jobs to Computerisation?’ which estimated that 47% of jobs in the US are at risk of automation.

In this talk Dr Carl Benedikt Frey, Co-Director of the Oxford Martin Programme on Technology and Employment, will discuss the societal consequences of the accelerating pace of automation, and what we can learn from previous episodes of worker-replacing technological change.

This is a joint lecture with The Rockefeller Foundation Economic Council on Planetary Health at the Oxford Martin School

Cooling is critical for many of the sustainable development goals, including those relating to health, shelter, livelihoods, education and nutrition. As the world’s population grows, as disposable incomes grow and as urban areas grow, the need for cooling is booming. However cooling uses super polluting gases and large amounts of energy and is therefore a significant cause of climate change. More efficient, clean cooling has the potential to avoid up to a degree of warming by the end of the century and recently all governments came together to agree action to try to maximize this opportunity. Cooling sits at the intersection of the UNFCCC, the SDGs and the Montreal Protocol, but can these forces ensure success?

Dan Hamza-Goodacre will explain the risks and possibilities in the search for sustainable cooling for all.

This talk will be followed by a drinks reception, all welcome

Currently limited tools exist to accurately forecast the complex nature of disease spread across the globe. Dr Moritz Kraemer will talk about the dynamic global maps being built, at 5km resolution, to predict the invasion of new organisms under climate change conditions and continued unplanned urbanisation.

DANSOX presents a one-day conference on the life and work of the great 20th-century choreographer, Sir Kenneth MacMillan (1929-1992). MacMillan stands among the great innovators of his time in theatre, film, art, and music. The conference will discuss his work, the challenges of preserving the record, explore little known early work, his literary and musical choices, design, and choreographic method.

Guest speakers include: the artist and widow of Sir Kenneth, Lady MacMillan; the former Principal and Director of the Royal Ballet, Dame Monica Mason; the music expert, Natalie Wheen; and choreologist, Anna Trevien. Dancers, artists, and filmmakers who worked with Kenneth will join the conversation. A performance/lecture of the reconstruction of ‘Playground’ with Yorke Dance will be held in the JdP at the end of the conference.

Dung beetles in the British Isles are a vital part of their associated ecosystems but have been historically rather overlooked probably due to their chosen habitat. Now our native dung beetles are finally beginning to get some of the invertebrate limelight due to an emphasis on ecosystem services and a much more environmentally friendly farming future. However we are lacking on a great deal of base data about these vitally important species and surveying is the one of the best ways to get information. This means getting into dung and discovering these unsung heroes

Carlos Lopes will deliver an overview of the critical development issues facing the African continent today. He will talk about a blueprint of policies to address issues, and an intense, heartfelt meditation on the meaning of economic development in the age of democratic doubts, identity crises, global fears and threatening issues of sustainability.

This talk will be followed by a book signing and drinks reception, all welcome.

The ecology and history of one of the largest atolls in the world. Aldabra, situated in the South West Indian Ocean, supports the largest population of giant tortoises worldwide. A UNESCO World Heritage Site, it is a stronghold for wildlife in a region that is besieged by threats.

Professor Dave Carter reveals how understanding intercellular communication could improve healthcare.

This is a joint event with the Oxford Martin Programme on the Future of Food

Dr Mike Hamm will explore the opportunity for regional food systems in-and-around cities for mutual benefit. He will approach a number of issues – including vertical farming, bio-geochemical cycles, water use, new entry farmers, and healthy food provisioning – embedded in the notion of city region food systems with reference to supply/demand dynamics.

This talk will be followed by a drinks reception, all welcome

In Origin of Species, Charles Darwin described how a population explosion occurs and called the time of population explosion “ favourable seasons”, he was not to know it, but such circumstances arose for his own species at around the time of his own birth. However, the favourable seasons for human population growth were not experienced favourably, with times of great social dislocation from small scale enclosure to global colonisation. Now those seasons are over, we have experienced the first ever sustained slowdown in the rate of global human population growth. This has been the case for at least one human generation. However, we are not just slowing down in terms of how many children we have, but in almost everything else we do, other than in the rise in global temperatures that we are recording and that we have to live with. It can be argued that there is even a slowdown in such unexpected areas as debt, publishing, and in the total amount useful information being produced.

If this is true – that humanity is slowing down in almost everything that we do – what does this mean? What measurements suggest that slowdown is true? And if so much is still rising, albeit at slower and slower rates – is that such a great change? Finally how might the slowdown impact on economic thought. In many ways economics was the science of the great acceleration; a science that makes most sense when markets are expanding and demand is rising. What kind of an economics is needed in a world where enormous and accelerating growth has stopped being the normality?

Coriander Theatre presents a new play ‘My Mother Runs in Zig-Zags’ at the North Wall Arts Centre, 30th May – 1st June 2019, 7:30pm, Saturday Matinee 2:30pm.

Sometimes, race and trauma are like leaky old pipes: you can’t even have a friend over for dinner without something spilling out everywhere and flooding your life in the most unexpected way.

A conversation between friends becomes a journey to the Lebanese and Nigerian civil wars. Half-remembered worlds of violent oral history invade the kitchen and layer themselves over everyday life, shining light on the laughter that heals intergenerational traumas, and celebrating the overflowings and excesses of a life shaped by migration.

With an original musical score, a chorus of performance poets and contemporary dancers, and stories passed on from a generation of migrants, My mother runs in zig-zags is a bold new tragicomedy, devised by the best of Oxford University’s BAME actors and performers.

Age Guidance: 12+

My mother runs in zig zags

Our wild bees and other pollinators are so important, but they are still the unsung heroes of the environment, gardens and countryside and continue to decline in number and range. The talk will identify what we can all do to help wild bees. Many of the actions we take to protect one pollinator species, such as flower rich habitat creation and reduction in pesticide use, will assist biodiversity as a whole.

The high seas are under severe pressure from both direct and indirect human impacts, including the effects of over-fishing, plastic debris and climate change. In this talk, Prof Alex Rogers will present what a network of marine protected areas in the high seas might look like, protecting 30% of known conservation features and taking into account climate change impacts. We will also hear from Dr Gwilym Rowlands, who will consider how such a network of marine protected areas could be enforced and the potential benefits to the ocean.

Professor Sir Paul Collier and Professor Colin Mayer CBE will share the latest thinking and research into the future of capitalism and the corporation to understand how business might be changed to make it work better for society. The speakers will bring together their new books, The Future of Capitalism: Facing The New Anxieties and Prosperity: Better Business Makes the Greater Good, alongside the British Academy’s Future of the Corporation programme research to pose serious questions of our economic system.

This talk will be followed by a drinks reception, book sale and signing, all welcome

This is a joint book talk with The Rockefeller Foundation Economic Council on Planetary Health at the Oxford Martin School

Now that Trump has turned the United States into a global climate outcast, will China take the lead in saving our planet from environmental catastrophe? Many signs point to yes. China, the world’s largest carbon emitter, is leading a global clean energy revolution, phasing out coal consumption and leading the development of a global system of green finance.

But as leading China environmental expert and author of Will China Save the Planet? Barbara Finamore will explain in this talk, it is anything but easy. The fundamental economic and political challenges that China faces in addressing its domestic environmental crisis threaten to derail its low-carbon energy transition. Yet there is reason for hope. China’s leaders understand that transforming the world’s second largest economy from one dependent on highly polluting heavy industry to one focused on clean energy, services and innovation is essential, not only to the future of the planet, but to China’s own prosperity.

We will also hear from respondent Radhika Khosla, Research Director at the Oxford India Centre for Sustainable Development, Somerville College.

This talk will be followed by a drinks reception, book sale and signing, all welcome

The biosphere and econosphere are deeply interlinked and both are in crisis. Industrial, fossil-fuel based capitalism delivered major increases in living standards from the mid-18th through late-20th centuries, but at the cost of widespread ecosystem destruction, planetary climate change, and a variety of economic injustices. Furthermore, over the past 40 years, the gains of growth have flowed almost exclusively to the top 10%, fuelling populist anger across many countries, endangering both democracy and global action on climate change.

This talk will argue that underlying the current dominant model of capitalism are a set of theories and ideologies that are outdated, unscientific, and morally unsound. New foundations can be built from modern understandings of human behaviour, complex systems science, and broad moral principles. By changing the ideologies, narratives, and memes that govern our economic system, we can create the political space required for the policies and actions required to rapidly transform to a sustainable and just economic system.

Dr Larkman is a retired Oxford biologist who has been chairman of OOS for the last 5 years. His main interest is the precipitous decline in the UK’s small, seed-eating farmland birds over the last 50 years.

The ability to accurately identify and interpret Track and Sign rests on a body of traditional knowledge that previous generations of naturalists would have regarded as fundamental. Sadly, now it is largely unknown and untaught, but with the upsurge of Citizen Science, it is perhaps more relevant than ever.

Slime moulds thrive in damp woodlands and normally spread over rotting logs eating bacteria and fungi. They are also unusual in being single giant cells that show remarkably sophisticated behaviour considering their humble form. This talk presents a little vignette of the science behind these curious beasts and how it has led to better understanding of other networked systems, and even the origins of civilisation.

An amusing talk and exploration of AI and the future of technology. Is the future more absurd than comedians can imagine? Will a driver-less BMW still cut you up? What do we do when a human doesn’t pass the Turing test? Computers have beaten chess masters but can they beat comedians?

We cannot end poverty without ending energy poverty. Ever since the world’s first power plants whirred to life in 1882, we have seen how electricity is the lynchpin for development in all of its forms.

Manufacturing and industrial productivity, agriculture and food security, nutrition, hygiene, water, public health, education, even community engagement, in other words, daily life in a modern economy, demand access to reliable energy.

And yet despite significant progress over nearly 140 years, more than 800 million people around the world live without access to electricity, and hundreds of millions more struggle with unreliable or unaffordable service. Families are deprived of the means to labour productively and their quality of life and status in extreme poverty goes unchanged.

We need urgently to fast-track sustainable power solutions, investments, and partnerships across the globe to catalyze an energy transformation and accelerate sustainable, reliable and modern electrification for economic development.

In this book talk the Author, Carl Benedikt Frey, will discuss how the Industrial Revolution was a defining moment in history, but how few grasped its enormous consequences at the time. Now that we are in the midst of another technological revolution how can the lessons of the past can help us to more effectively face the present?

This talk will be followed by a book sale, signing and drinks reception. All welcome.

Data-driven micro-targeted campaigns have become a main stable of political strategy. As personal and societal data becomes more accessible, we need to understand how it can be used and mis-used in political campaigns and whether it is relevant to regulate political candidates’ access to data.

This book talk will be followed by a drinks reception and book sale, all welcome

Bernard Tucker Memorial Lecture – Joint with Oxford Ornithological Society