The AfOx insaka is a gathering for sharing ideas and knowledge about Africa-focused research with speakers from diverse and varied academic disciplines. There are two events each term.

Speakers for the first AfOx insaka in the new academic year are Dr Robtel Neajai Pailey, Leverhulme Early Career Fellow, Oxford Department of International Development and Dr Jacob McKnight, Senior Researcher, Centre for Tropical Medicine and Global Health.

At this AfOx talk, Robtel Neajai Pailey uses her anti-corruption children’s books to argue that equipping children with verbal tools to question the confusing ethical codes of adults can revolutionise how we talk and theorise about corruption.

Jake McKnight is a Health Systems Researcher at the Oxford Health Systems Collaboration (OHSCAR). He was originally a logistician for MSF in Angola and Somalia, before conducting his PhD research in Ethiopia. He then read for the MSc. in African Studies at Oxford, before completing his PhD at Said Business School, where he concentrated on healthcare reform in Ethiopia. Jake will talk about the failures and successes of projects he’s studied or been involved in, reflecting on the idea that ‘Africa Works’, and as researchers and implementors, it’s up to us to fit local cultures rather to try to ‘fix’ them.

As part of the Surgical Grand Round lecture series, hosted by the Nuffield Department of Surgical Sciences, Professor Chris Lavy from the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences will present ‘Public-private partnerships in elective surgery’.

The logic and principles behind the drive for evidence-based health care are so compelling that often the limitations of evidence go unacknowledged. Despite a strong evidence base demonstrating the health risks associated with higher body weights, and health professionals routinely instructing patients to lose weight to improve their health, the incidence of obesity is predicted to continue to rise. Calling on his research into the relationships between obesity, inequality and health, Oli Williams – a fellow of The Healthcare Improvement Studies Institute – will argue that when it comes to reducing the burden on, and improving, health care a more critical approach to the way we generate, select, apply and communicate evidence is needed.

Oli Williams completed his PhD in the Department of Sociology at the University of Leicester. He was subsequently awarded the NIHR CLAHRC West Dan Hill Fellowship in Health Equity which he held at the University of Bath. He later re-joined the University of Leicester in the Department of Health Sciences working in the SAPPHIRE Group and is now based at King’s College London after being awarded a THIS Institute Postdoctoral Fellowship. His research focuses on health inequalities, the promotion of healthy lifestyles, obesity, weight stigma, equitable intervention and co-production. He co-founded the art collective Act With Love (AWL) to promote social change. The Weight of Expectation comic is one example of their work, view others at: www.actwithlove.co.uk In recognition of his work on weight stigma the British Science Association invited Oli to deliver the Margaret Mead Award Lecture for Social Sciences at the British Science Festival 2018.

This talk is being held as part of the Qualitative Research Methods course which is part of the Evidence-Based Health Care Programme. This is a free event and members of the public are welcome to attend.

Join us to learn about the progress being made in biomaterials, the next generation of innovative solutions that aim to tackle current health challenges, and what it takes to start your own venture. The event will feature talks from two prominent individuals, Dr Nick Skaer (CEO of Orthox) and Dr Nick Edwards (Co-Founder of MedInnovate and Chairman of Satie8). Dr Skaer has over 25 years’ experience in life science and materials research, and 14 years as a medtech CEO, raising over £18m. Dr Edwards has over 30 years’ experience in supporting pharmaceutical companies as ex- Global Lead of Accenture’s Pharmaceutical R&D business and current Chairman of Prescient Healthcare Group. He is a Founder of MedInnovate and an investor and supporter of life-science start-ups as well as current Chairman of Satie8.

There will be a networking & drinks reception after the event.

The event is free as always. Spots are limited, so get registered today on:

https://www.eventbrite.co.uk/e/the-next-generation-of-medical-devices-tickets-76955848013

This is an exclusive event brought to you by the SIU in partnership with the Oxford Pharmacology Society. The application of big data and genomics in healthcare is vast, with tremendous opportunities to revolutionise current methods of diagnosing and treating diseases. Although, patient specific data is a powerful tool that can accelerate the development and translation of novel drugs and therapeutics, there are limitations to overcome. This event will take a closer look at the role of industries, academics, clinicians and healthcare policy makers in encouraging the translation of ideas into real-world solutions and the challenges within each sector. To discuss this, we will be hosting Dr Jeffrey Barrett (CSO and Director of Genomics Plc), Dr Michelle van Velthoven (Sir David Cooksey Fellow in Healthcare Translation at the University of Oxford) and Dr Amitava Banerjee (Associate Professor in Clinical Data Science at University College London).
The event will be on the 20th November at 17h30pm – 19h00, in the Department of Pharmacology. There will be a free networking & drinks reception after the event.
The event is free as always. Spots are limited, so get registered today on https://www.eventbrite.co.uk/e/pharma-and-big-data-the-healthcare-revolution-tickets-80628276345

The talk will provide an overview of dragonflies and their life cycles and habitats as well illustrating a number of species that occur in England including those that are currently colonising from the Continent and increasing in numbers.

Tara Pirie recalls her three years living in a tent, while tracking and gathering data on these elusive, but beautiful big cats. She is now one of the world’s leading experts on Leopard ecology and conservation.

Should doctors with commercial interests lead research on their products? Should we forget ‘conflicts’ and discuss ‘declarations of interest’ instead? Who should hold and maintain conflicts of interest registers for doctors? Should practicing doctors work with the pharma industry as well as serve on guideline committees? Should researchers with extensive financial interests be disqualified from studies of their own products?

The Physician Payments Sunshine Act requires US manufacturers to collect, track and report all financial relationships with clinicians and teaching hospitals. Professor Heneghan will discuss the failings with the current system of reporting of conflicts in medicine, what’s been tried so far, and why it is time for a UK Sunshine Act.

Carl Heneghan, Professor of Evidence-Based Medicine, employs evidence-based methods to research diagnostic reasoning, test accuracy and communicating diagnostic results to a wider audience.

This talk is being held as part of the Practice of Evidence-Based Health Care module which is part of the MSc in Evidence-Based Health Care and the MSc in EBHC Systematic Reviews. Members of the public are welcome to attend.

Warburg Memorial Lecture – Joint with BBOWT
Volunteer-based botanical monitoring has been a mainstay of British and Irish botany for decades, but only recently has a recording scheme for plant communities been established. Dr Pescott outlines the history of this new National Plant Monitoring Scheme, with a particular focus on the challenges and rewards that have been associated with establishing this novel approach in the UK.

Overdiagnosis is the diagnosis of “disease” that will never cause symptoms or death during a patient’s lifetime.

Recent results of the NELSON Lung Cancer Screening Trial reports reductions in lung-cancer survival but not overall survival – The desire to detect disease even earlier means Overdiagnosis is on the rise, however, the interpretation of screening trial results is problematic and often gives rise to significant uncertainties that go unanswered.

Carl Heneghan, Professor of Evidence-Based Medicine, employs evidence-based methods to research diagnostic reasoning, test accuracy and communicating diagnostic results to a wider audience.

This talk is being held as part of the Evidence-Based Diagnosis & Screening module which is part of the MSc in Evidence-Based Health Care and the MSc in EBHC Medical Statistics. Members of the public are welcome to attend.

In this book talk, Claas will review central findings of his research on the past 80 years of antibiotic use, resistance, and regulation in food production with introduction by Prof Mark Harrison, Director of Wellcome Centre for Ethics and Humanities.

Mass-introduced after 1945, antibiotics helped revolutionise food production. Farmers and veterinarians used antibiotics to prevent and treat disease, protect plants, preserve food, and promote animals’ growth. Many soon became dependent on routine antibiotic use to sustain and increase production. The resulting growth of antibiotic infrastructures came at a price. Critics blamed antibiotics for leaving dangerous residues in food, enabling bad animal welfare, and selecting for antimicrobial resistance (AMR) in bacteria, which could no longer be treated with antibiotics.

Pyrrhic Progress analyses over 80 years of evolving non-human antibiotic use on both sides of the Atlantic and introduces readers to the historical and current complexities of antibiotic stewardship in a time of rising AMR.

This talk includes a drinks reception and nibbles, all welcome

Blackwell’s are delighted to be joined by Petina Gappah to discuss her latest novel, Out of Darkness, Shining Light.

Synopsis

Petina Gappah’s epic journey through nineteenth-century Africa – following the funeral caravan who bore Bwana Daudi’s body – is ‘engrossing, beautiful and deeply imaginative.’ (Yaa Gyasi)

This is the story of the body of Bwana Daudi, the Doctor, the explorer David Livingstone – and the sixty-nine men and women who carried his remains for 1,500 miles so that he could be borne across the sea and buried in his own country.

The wise men of his age say Livingstone blazed into the darkness of their native land leaving a track of light behind where white men who followed him could tread in perfect safety. But in Petina Gappah’s radical novel, it is those in the shadows of history – those who saved a white man’s bones; his dark companions; his faithful retinue on an epic funeral march – whose voices are resurrected with searing intensity.

This final, fateful journey across the African interior is lead by Halima, Livingstone’s sharp-tongued cook, and three of his most devoted servants: Jacob, Chuma and Susi. Their tale of how his corpse was borne out of nineteenth-century Africa – carrying the maps that sowed the seeds of the continent’s brutal colonisation – has the power of myth. It is not only symbolic of slavery’s hypocrisy, but a portrait of a world trembling on the cusp of total change – and a celebration of human bravery, loyalty and love.

Petina Gappah is a Zimbabwean writer with law degrees from Cambridge, Graz University and the University of Zimbabwe. Her short fiction and essays have been published in eight countries. Her debut story collection, An Elegy for Easterly, won the Guardian First Book Award in 2009, and her first novel, The Book of Memory, was longlisted for the 2015 Bailey’s Women’s Prize for Fiction.

This event is free, but please do register if you plan on attending. Please note, this event may take place in the Philosophy Department which is accessible via a short flight of stairs. Seats are unallocated. For more information, please contact our Customer Service Department on 01865 333 623 or email events.oxford@blackwell.co.uk

In modern high-tech health care, patients appear to be the stumbling block.

Uninformed, anxious, noncompliant individuals with unhealthy lifestyles who demand treatments advertised by celebrities and insist on unnecessary but expensive diagnostics may eventually turn into plaintiffs. But what about their physicians? About ten years ago, Muir Gray and Gerd Gigerenzer published a book with the subtitle “Envisioning health care 2020”. They listed “seven sins” of health care systems then, one of which was health professionals’ stunning lack of risk literacy. Many were not exactly sure what a false-positive rate was, or what overdiagnosis and survival rates mean, and they were unable to evaluate articles in their own field. As a consequence, the ideals of informed consent and shared decision-making remain a pipedream – both doctors and patients are habitually misled by biased information in health brochures and advertisements. At the same time, the risk literacy problem is one of the few in health care that actually have a known solution. A quick cure is to teach efficient risk communication that fosters transparency as opposed to confusion, both in medical school and in CME. It can be done with 4th graders, so it should work with doctors, too.

Now, in 2020, can every doctor understand health statistics? In this talk, Gerd Gigerenzer will describe the efforts towards this goal, a few successes, but also the steadfast forces that undermine doctors’ ability to understand and act on evidence. Moreover, the last decade has seen two new forces that distract from solving the problem. The first is the promise of digital technology, from diagnostic AI systems to big data analytics, which consumes much of the attention. Digital technology is of little help if doctors do not understand it. Second, our efforts to make patients competent and to encourage them to articulate their values are now in conflict with the new paternalistic view that patients just need to be nudged into better behaviour.

This talk will be followed by a drinks reception, all welcome

Joint event with: The Oxford–Berlin Research Partnership

Lecture by Jinny Blom who has created over 250 gardens and landscapes, Laurent-Perrier garden which gained a Gold at Chelsea. Artist in Residence for Chelsea & Westminster Hospital, she is author of The Thoughtful Gardener: An intelligent approach to garden design (2017). Pay at the door; registration not required.

With the UK population predicted to grow nearly 20% by 2050 (circa 77 million people), over 65s making up around 25% of the population and more and more demands being put on the healthcare system what does the future hold?

Professor Chris Whitty, England’s Chief Medical Officer, will discuss predictions for the future advancement of healthcare in the UK and how these advancements will monitor, diagnose and treat us and how this will change our healthcare system.

Part of the Oxford Martin School Lecture Series: ‘Shaping the future’

We speak of earthquakes, floods, and fires as wild and untameable disasters – natural phenomena that spring unexpectedly from a hostile landscape and challenge our trust in the safety of our homes. But Ilan Kelman states otherwise. Join him as he challenges the inevitability of these disasters, suggesting that human decisions to build on flood plains, deforest territories, and impose upon the environment for social, political or economic reasons create or exacerbate these disasters. And he has some suggestions on how we can and should act to stop people suffering when nature unleashes its powers.

Ilan Kelman is Professor of Disasters and Health at University College London and a Professor at the University of Agder, Kristiansand in Norway. His overall research interest is linking disasters and health, including the integration of climate change into disaster research and health research. Suitable for ages 14+

Twitter @IlanKelman

Snakebite is arguably the world’s biggest hidden health crisis. It kills some 120,000 people every year, mostly from the world’s poorest communities in rural Africa, Asia and South America. The burden of death and disability is equivalent to that of prostate cancer or cervical cancer and greater than that of any other neglected tropical disease. Yet the problem is solvable – we need to bring snakebite treatment into the 21st century; we need innovative approaches to discovering and developing next generation snakebite treatments; and we need to build and importantly, sustain snakebite as a global health priority.

Dr Nick Cammack was appointed to the Wellcome Trust in September 2019 to lead an ambitious new £80 million programme aimed at driving a step-change in snakebite treatment around the world. The goal is to achieve a 50% reduction in mortality by 2030. In addition there is a pressing need to modernise the production of anti-venoms and improve their means of delivery.

Talk, followed by walking tour of the park. Jane Kilsby, local historian shares her
recent research into this well-loved 19th century public park. Maximum 20

Adults make choices regarding the technology they use to self-manage their health and wellbeing, and these technologies are often adopted, used and abused in ways that researchers, manufacturers, and clinicians have not accounted for. This talk will give an overview of human-computer interaction qualitative research on the real world use of mobile technologies in people’s everyday lives. Accounting for individual health and wellbeing choices adults make with technology, supporting choices through end user customisation, and the emerging trend towards Do-It-Yourself open-source health and wellbeing technology will be discussed. Examples of pragmatic qualitative studies will be given from research on wearables, apps, and standalone devices used for Type 1 diabetes, hearing loss, baby monitoring, and physical fitness.

Dr Aisling O’Kane is a Senior Lecturer in Human-Computer Interaction for Health and Deputy Director of the EPSRC CDT in Digital Health and Care at the University of Bristol. As a member of the Bristol Interaction Group and the Digital Health Engineering Group, she uses a pragmatic approach to qualitative research of health, wellbeing and care technologies. Dr O’Kane is currently PI of Innovate UK Machine Learning for Diabetes, co-designing AI to support diabetes self-management and Co-I of EPSRC SPHERE Next Steps, co-designing smart home technology to support health at home.

This talk is being held as part of the Advanced Qualitative Research Methods course which is part of the Evidence-Based Health Care Programme. This is a free event and members of the public are welcome to attend.

How the Freshwater Habitats Trust’s ‘Saving Oxford’s Wetland Wildlife’ project is helping to improve and monitor Oxford’s valuable freshwater areas, and protect the species they support.

In recent years there have been some alarming media stories about declines in insect populations. This talk provides an overview of trends in British insect populations over the past four decades.

Lecture by Linda Farrar, a freelance researcher, lecturer and author of Ancient Roman Gardens. The art of gardening has a long history, with gardens being used in most ancient cultures to enhance living areas, and even public spaces. We will look at examples from a range of ancient societies. Pay at the door or book online

To enhance our natural environment, we need to put the environment
back into the heart of the economy. Using natural capital as the
guiding principle, we can leave a better environment for future
generations, implementing a bold 25 year environment plan, thereby
restoring rivers, greening agriculture, putting nature back into towns
and cities, and restoring the uplands and our marine ecosystems. We
can put the carbon back into the soils, encourage natural carbon
sequestration, rebuild our biodiversity and improve our mental and
physical health. This is the prize – a Green and Prosperous Land – and
it is much more economically efficient than the dismal proposed of
business-as-usual and allowing the declines of the last century to
continue.

Tea/coffee, biscuits on arrival in the Committee Room. Introductory talk from Sophie Huxley, Gardener, LMH, followed by tour of the garden. Parking for 5 cars only (priority to Blue Card holders). Maximum 20 persons

Friday 23 October

Lecture by Advolly Richmond. Thomas Birch was a trained botanist, and
head gardener at Orwell Park, Ipswich, before travelling to the Gold Coast.
He became part of the international network of correspondents and plant
collectors relied upon by the Royal Botanic Gardens at Kew. This talk aims to
reveal the true extent of Birch Freeman’s horticultural and botanical legacy.
Pay at the
door: £5 (members) £8 (guests

Join Professor Chas Bountra, Professor of Translational Medicine and Professor Sir Charles Godfray as they discuss how the healthcare system has had to adapt due to the Covid-19 pandemic and what this means in the future.

Lecture by Hanna Zembrzycka-Kisiel, Principal Major Applications Officer at
South Oxfordshire and Vale of White Horse Councils. Hanna uses the research
insights of her recent MA Thesis to explore the reality of poor urban design
and the benefits of green spaces in our living environments, drawing on local
and international urban design projects for inspiration. Book online or pay at the door.

With COVID-19 vaccines on the horizon, attention again returns to the contentious topic of whether vaccination should be made mandatory.

Recent polling has resulted in worrying headlines about a lack of willingness to have a COVID-19 vaccine if it were available.

Are mandates the answer to ensure vaccine high uptake to end the pandemic? While still a hypothetical scenario, without yet having a safe and effective vaccine approved for use, this could change in the coming months. The question of introducing mandatory vaccination spans considerations of personal liberty, health decision-making, public health and policy, as well as the relationship between the state and its citizens. Join Professor Julian Savulescu and Dr Samantha Vanderslott to debate the ethical and public policy arguments for and against mandatory COVID-19 vaccination.

On the 30th November it was announced that the Artificial Intelligence computer programme AlphaFold had made a decisive breakthrough in the determination of the 3-D structures of proteins.

The announcement was immediately hailed as one of the major scientific advances of the decade.

Why is it important to understand the 3-D structures of protein, why are they difficult to construct, and what is the nature of AlphaFold’s advance? Why is this so exciting and what further advances in medicine and the other biosciences may result? To find out, join a conversation between Yvonne Jones, Director, Cancer Research UK Receptor Structure Research Group and Charles Godfray, Director, Oxford Martin School, who will explore these fascinating issues.

Lecture by Jane Owen, preceded by OGT’s Christmas drinks party.
Jane Owen, Founder Member of OGT, avid gardener, garden historian and
previously Deputy Editor of the Financial Times, gives us her personal take on
garden history – not to be missed! Doors open 6.30pm for wine or juice (inc), for lecture at 7pm. Book online or pay at the door.
door