As part of the Surgical Grand Round lecture series, hosted by the Nuffield Department of Surgical Sciences, Professor Chris Lavy from the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences will present ‘Public-private partnerships in elective surgery’.

The logic and principles behind the drive for evidence-based health care are so compelling that often the limitations of evidence go unacknowledged. Despite a strong evidence base demonstrating the health risks associated with higher body weights, and health professionals routinely instructing patients to lose weight to improve their health, the incidence of obesity is predicted to continue to rise. Calling on his research into the relationships between obesity, inequality and health, Oli Williams – a fellow of The Healthcare Improvement Studies Institute – will argue that when it comes to reducing the burden on, and improving, health care a more critical approach to the way we generate, select, apply and communicate evidence is needed.

Oli Williams completed his PhD in the Department of Sociology at the University of Leicester. He was subsequently awarded the NIHR CLAHRC West Dan Hill Fellowship in Health Equity which he held at the University of Bath. He later re-joined the University of Leicester in the Department of Health Sciences working in the SAPPHIRE Group and is now based at King’s College London after being awarded a THIS Institute Postdoctoral Fellowship. His research focuses on health inequalities, the promotion of healthy lifestyles, obesity, weight stigma, equitable intervention and co-production. He co-founded the art collective Act With Love (AWL) to promote social change. The Weight of Expectation comic is one example of their work, view others at: www.actwithlove.co.uk In recognition of his work on weight stigma the British Science Association invited Oli to deliver the Margaret Mead Award Lecture for Social Sciences at the British Science Festival 2018.

This talk is being held as part of the Qualitative Research Methods course which is part of the Evidence-Based Health Care Programme. This is a free event and members of the public are welcome to attend.

Join us to learn about the progress being made in biomaterials, the next generation of innovative solutions that aim to tackle current health challenges, and what it takes to start your own venture. The event will feature talks from two prominent individuals, Dr Nick Skaer (CEO of Orthox) and Dr Nick Edwards (Co-Founder of MedInnovate and Chairman of Satie8). Dr Skaer has over 25 years’ experience in life science and materials research, and 14 years as a medtech CEO, raising over £18m. Dr Edwards has over 30 years’ experience in supporting pharmaceutical companies as ex- Global Lead of Accenture’s Pharmaceutical R&D business and current Chairman of Prescient Healthcare Group. He is a Founder of MedInnovate and an investor and supporter of life-science start-ups as well as current Chairman of Satie8.

There will be a networking & drinks reception after the event.

The event is free as always. Spots are limited, so get registered today on:

https://www.eventbrite.co.uk/e/the-next-generation-of-medical-devices-tickets-76955848013

This is an exclusive event brought to you by the SIU in partnership with the Oxford Pharmacology Society. The application of big data and genomics in healthcare is vast, with tremendous opportunities to revolutionise current methods of diagnosing and treating diseases. Although, patient specific data is a powerful tool that can accelerate the development and translation of novel drugs and therapeutics, there are limitations to overcome. This event will take a closer look at the role of industries, academics, clinicians and healthcare policy makers in encouraging the translation of ideas into real-world solutions and the challenges within each sector. To discuss this, we will be hosting Dr Jeffrey Barrett (CSO and Director of Genomics Plc), Dr Michelle van Velthoven (Sir David Cooksey Fellow in Healthcare Translation at the University of Oxford) and Dr Amitava Banerjee (Associate Professor in Clinical Data Science at University College London).
The event will be on the 20th November at 17h30pm – 19h00, in the Department of Pharmacology. There will be a free networking & drinks reception after the event.
The event is free as always. Spots are limited, so get registered today on https://www.eventbrite.co.uk/e/pharma-and-big-data-the-healthcare-revolution-tickets-80628276345

Inaugural event in our new events series focusing on responsible leadership: Driving Diversity and Inclusion Seminar Series.

Progress on diversity in the UK civil service and why it matters. How the dial only really shifted on gender, and why the focus is now on inclusion and addressing bullying and harassment. What the good leaders are doing?

Dame Sue Owen will give a talk followed by a Q&A with the audience moderated by Sue Dopson, Rhodes Trust Professor of Organisational Behaviour, Fellow of Green Templeton College, Deputy Dean of Saïd Business School.

Event Schedule:
17:15 – Registration opens
17:45 – Event starts
18:45 – Drinks reception
19:45 – Close

Should doctors with commercial interests lead research on their products? Should we forget ‘conflicts’ and discuss ‘declarations of interest’ instead? Who should hold and maintain conflicts of interest registers for doctors? Should practicing doctors work with the pharma industry as well as serve on guideline committees? Should researchers with extensive financial interests be disqualified from studies of their own products?

The Physician Payments Sunshine Act requires US manufacturers to collect, track and report all financial relationships with clinicians and teaching hospitals. Professor Heneghan will discuss the failings with the current system of reporting of conflicts in medicine, what’s been tried so far, and why it is time for a UK Sunshine Act.

Carl Heneghan, Professor of Evidence-Based Medicine, employs evidence-based methods to research diagnostic reasoning, test accuracy and communicating diagnostic results to a wider audience.

This talk is being held as part of the Practice of Evidence-Based Health Care module which is part of the MSc in Evidence-Based Health Care and the MSc in EBHC Systematic Reviews. Members of the public are welcome to attend.

Overdiagnosis is the diagnosis of “disease” that will never cause symptoms or death during a patient’s lifetime.

Recent results of the NELSON Lung Cancer Screening Trial reports reductions in lung-cancer survival but not overall survival – The desire to detect disease even earlier means Overdiagnosis is on the rise, however, the interpretation of screening trial results is problematic and often gives rise to significant uncertainties that go unanswered.

Carl Heneghan, Professor of Evidence-Based Medicine, employs evidence-based methods to research diagnostic reasoning, test accuracy and communicating diagnostic results to a wider audience.

This talk is being held as part of the Evidence-Based Diagnosis & Screening module which is part of the MSc in Evidence-Based Health Care and the MSc in EBHC Medical Statistics. Members of the public are welcome to attend.

In this book talk, Claas will review central findings of his research on the past 80 years of antibiotic use, resistance, and regulation in food production with introduction by Prof Mark Harrison, Director of Wellcome Centre for Ethics and Humanities.

Mass-introduced after 1945, antibiotics helped revolutionise food production. Farmers and veterinarians used antibiotics to prevent and treat disease, protect plants, preserve food, and promote animals’ growth. Many soon became dependent on routine antibiotic use to sustain and increase production. The resulting growth of antibiotic infrastructures came at a price. Critics blamed antibiotics for leaving dangerous residues in food, enabling bad animal welfare, and selecting for antimicrobial resistance (AMR) in bacteria, which could no longer be treated with antibiotics.

Pyrrhic Progress analyses over 80 years of evolving non-human antibiotic use on both sides of the Atlantic and introduces readers to the historical and current complexities of antibiotic stewardship in a time of rising AMR.

This talk includes a drinks reception and nibbles, all welcome

Blackwell’s are delighted to be joined by Petina Gappah to discuss her latest novel, Out of Darkness, Shining Light.

Synopsis

Petina Gappah’s epic journey through nineteenth-century Africa – following the funeral caravan who bore Bwana Daudi’s body – is ‘engrossing, beautiful and deeply imaginative.’ (Yaa Gyasi)

This is the story of the body of Bwana Daudi, the Doctor, the explorer David Livingstone – and the sixty-nine men and women who carried his remains for 1,500 miles so that he could be borne across the sea and buried in his own country.

The wise men of his age say Livingstone blazed into the darkness of their native land leaving a track of light behind where white men who followed him could tread in perfect safety. But in Petina Gappah’s radical novel, it is those in the shadows of history – those who saved a white man’s bones; his dark companions; his faithful retinue on an epic funeral march – whose voices are resurrected with searing intensity.

This final, fateful journey across the African interior is lead by Halima, Livingstone’s sharp-tongued cook, and three of his most devoted servants: Jacob, Chuma and Susi. Their tale of how his corpse was borne out of nineteenth-century Africa – carrying the maps that sowed the seeds of the continent’s brutal colonisation – has the power of myth. It is not only symbolic of slavery’s hypocrisy, but a portrait of a world trembling on the cusp of total change – and a celebration of human bravery, loyalty and love.

Petina Gappah is a Zimbabwean writer with law degrees from Cambridge, Graz University and the University of Zimbabwe. Her short fiction and essays have been published in eight countries. Her debut story collection, An Elegy for Easterly, won the Guardian First Book Award in 2009, and her first novel, The Book of Memory, was longlisted for the 2015 Bailey’s Women’s Prize for Fiction.

This event is free, but please do register if you plan on attending. Please note, this event may take place in the Philosophy Department which is accessible via a short flight of stairs. Seats are unallocated. For more information, please contact our Customer Service Department on 01865 333 623 or email events.oxford@blackwell.co.uk

In modern high-tech health care, patients appear to be the stumbling block.

Uninformed, anxious, noncompliant individuals with unhealthy lifestyles who demand treatments advertised by celebrities and insist on unnecessary but expensive diagnostics may eventually turn into plaintiffs. But what about their physicians? About ten years ago, Muir Gray and Gerd Gigerenzer published a book with the subtitle “Envisioning health care 2020”. They listed “seven sins” of health care systems then, one of which was health professionals’ stunning lack of risk literacy. Many were not exactly sure what a false-positive rate was, or what overdiagnosis and survival rates mean, and they were unable to evaluate articles in their own field. As a consequence, the ideals of informed consent and shared decision-making remain a pipedream – both doctors and patients are habitually misled by biased information in health brochures and advertisements. At the same time, the risk literacy problem is one of the few in health care that actually have a known solution. A quick cure is to teach efficient risk communication that fosters transparency as opposed to confusion, both in medical school and in CME. It can be done with 4th graders, so it should work with doctors, too.

Now, in 2020, can every doctor understand health statistics? In this talk, Gerd Gigerenzer will describe the efforts towards this goal, a few successes, but also the steadfast forces that undermine doctors’ ability to understand and act on evidence. Moreover, the last decade has seen two new forces that distract from solving the problem. The first is the promise of digital technology, from diagnostic AI systems to big data analytics, which consumes much of the attention. Digital technology is of little help if doctors do not understand it. Second, our efforts to make patients competent and to encourage them to articulate their values are now in conflict with the new paternalistic view that patients just need to be nudged into better behaviour.

This talk will be followed by a drinks reception, all welcome

Joint event with: The Oxford–Berlin Research Partnership

Lecture by Jinny Blom who has created over 250 gardens and landscapes, Laurent-Perrier garden which gained a Gold at Chelsea. Artist in Residence for Chelsea & Westminster Hospital, she is author of The Thoughtful Gardener: An intelligent approach to garden design (2017). Pay at the door; registration not required.

With the UK population predicted to grow nearly 20% by 2050 (circa 77 million people), over 65s making up around 25% of the population and more and more demands being put on the healthcare system what does the future hold?

Professor Chris Whitty, England’s Chief Medical Officer, will discuss predictions for the future advancement of healthcare in the UK and how these advancements will monitor, diagnose and treat us and how this will change our healthcare system.

Part of the Oxford Martin School Lecture Series: ‘Shaping the future’

Snakebite is arguably the world’s biggest hidden health crisis. It kills some 120,000 people every year, mostly from the world’s poorest communities in rural Africa, Asia and South America. The burden of death and disability is equivalent to that of prostate cancer or cervical cancer and greater than that of any other neglected tropical disease. Yet the problem is solvable – we need to bring snakebite treatment into the 21st century; we need innovative approaches to discovering and developing next generation snakebite treatments; and we need to build and importantly, sustain snakebite as a global health priority.

Dr Nick Cammack was appointed to the Wellcome Trust in September 2019 to lead an ambitious new £80 million programme aimed at driving a step-change in snakebite treatment around the world. The goal is to achieve a 50% reduction in mortality by 2030. In addition there is a pressing need to modernise the production of anti-venoms and improve their means of delivery.

Talk, followed by walking tour of the park. Jane Kilsby, local historian shares her
recent research into this well-loved 19th century public park. Maximum 20

Adults make choices regarding the technology they use to self-manage their health and wellbeing, and these technologies are often adopted, used and abused in ways that researchers, manufacturers, and clinicians have not accounted for. This talk will give an overview of human-computer interaction qualitative research on the real world use of mobile technologies in people’s everyday lives. Accounting for individual health and wellbeing choices adults make with technology, supporting choices through end user customisation, and the emerging trend towards Do-It-Yourself open-source health and wellbeing technology will be discussed. Examples of pragmatic qualitative studies will be given from research on wearables, apps, and standalone devices used for Type 1 diabetes, hearing loss, baby monitoring, and physical fitness.

Dr Aisling O’Kane is a Senior Lecturer in Human-Computer Interaction for Health and Deputy Director of the EPSRC CDT in Digital Health and Care at the University of Bristol. As a member of the Bristol Interaction Group and the Digital Health Engineering Group, she uses a pragmatic approach to qualitative research of health, wellbeing and care technologies. Dr O’Kane is currently PI of Innovate UK Machine Learning for Diabetes, co-designing AI to support diabetes self-management and Co-I of EPSRC SPHERE Next Steps, co-designing smart home technology to support health at home.

This talk is being held as part of the Advanced Qualitative Research Methods course which is part of the Evidence-Based Health Care Programme. This is a free event and members of the public are welcome to attend.

1/3: The case for a funded pension with a defined benefit (DB)

I begin by drawing attention to the efficiencies in the pooling of longevity and investment risk that collective funded pension schemes provide over individual defined contribution (IDC) pension pots in guarding against your risk of living too long. I then turn to an analysis of those collective schemes that promise a defined benefit (DB): an inflation-proof income in retirement until death, specified as a fraction of your salary earned during your career. I consider the concepts and principles within and beyond financial economics that underlie the valuation and funding of such a pension promise. I assess the merits of the ‘actuarial approach’ to funding an open, ongoing, enduring DB scheme at a low rate of contributions invested in ‘return-seeking’ equities and property. I also consider the merits of the contrasting ‘financial economics approach’, which calls for a higher rate of contributions set as the cost of bonds that ‘match’ the liabilities. I draw on the real-world case of the UK’s multi-employer Universities Superannuation Scheme (USS) to adjudicate between these approaches. The contrasting investment strategy of London’s SAUL pension scheme, the objectives of the Pensions Regulator, the significance of the Pension Protection Fund, and the decision of Trinity College Cambridge to withdraw from USS to protect itself against being the ‘last man standing’, all figure in the discussion.

Lecture 2: The case for collective defined contribution (CDC)
On any sensible approach to the valuation of a DB scheme, ineliminable risk will remain that returns on a portfolio weighted towards return-seeking equities and property will fall significantly short of fully funding the DB pension promise. On the actuarial approach, this risk is deemed sufficiently low that it is reasonable and prudent to take in the case of an open scheme that will be cashflow positive for many decades. But if they deem the risk so low, shouldn’t scheme members who advocate such an approach be willing to put their money where their mouth is, by agreeing to bear at least some of this downside risk through a reduction in their pensions if returns are not good enough to achieve full funding? Some such conditionality would simply involve a return to the practices of DB pension schemes during their heyday three and more decades ago. The subsequent hardening of the pension promise has hastened the demise of DB. The target pensions of collective defined contribution (CDC) might provide a means of preserving the benefits of collective pensions, in a manner that is more cost effective for all than any form of defined benefit promise. In one form of CDC, the risks are collectively pooled across generations. In another form, they are collectively pooled only among the members of each age cohorts.

Lecture 3: The case for an unfunded pay as you go (PAYG) pension

The previous two lectures grappled with various challenges that funded collective pension schemes face. In the final lecture, I ask whether an unfunded ‘pay as you go’ (PAYG) approach might provide a solution. With PAYG, money is directly transferred from those who are currently working to pay the pensions of those who are currently retired. Rather than drawing from a pension fund consisting of a portfolio of financial assets, these pensions are paid out of the Treasury’s coffers. The pension one is entitled to in retirement is often, however, a function of, even though not funded by, the pensions contributions one has made during one’s working life. I explore the extent to which a PAYG pension can be justified as a form of indirect reciprocity that cascades down generations. This contrasts with a redistributive concern to mitigate the inequality between those who are young, healthy, able-bodied, and productive and those who are elderly, infirm, and out of work. I explore claims inspired by Ken Binmore and Joseph Heath that PAYG pensions in which each generation pays the pensions of the previous generation can be justified as in mutually advantageous Nash equilibrium. I also discuss the relevance to the case for PAYG of Thomas Piketty’s claim that r > g, where “r” is the rate of return on capital and “g” is the rate of growth of the economy.

Lecture by Linda Farrar, a freelance researcher, lecturer and author of Ancient Roman Gardens. The art of gardening has a long history, with gardens being used in most ancient cultures to enhance living areas, and even public spaces. We will look at examples from a range of ancient societies. Pay at the door or book online

Tea/coffee, biscuits on arrival in the Committee Room. Introductory talk from Sophie Huxley, Gardener, LMH, followed by tour of the garden. Parking for 5 cars only (priority to Blue Card holders). Maximum 20 persons

This unusual online event will see Alberto Guibilini (Research Fellow, Uehiro Centre for Practical Ethics) and David Jones (Director, The Anscombe Bioethics Centre) adopting the other’s position on conscientious objection, arguing for the opposing view in an attempt to explore not only the subject, but the very nature of disagreement and discussion. Audience members will be encouraged to explore their views on conscientious objection in the same way.

We welcome questions in advance of the debate. To register on Zoom for the event please use the following link: https://us02web.zoom.us/webinar/register/WN_VrOGfqNrQVmw9k2KFz9HOA

This event is co-sponsored by the Anscombe Bioethics Centre in Oxford. It will start promptly at 6pm, and we expect to finish at 7:30pm.

Jointly organised by the Oxford Uehiro Centre for Practical Ethics and the Anscombe Bioethics Centre. This unusual online event will see Alberto Guibilini and David Jones adopting the other’s position on conscientious objection, arguing for the opposing view in an attempt to explore not only the subject, but the very nature of disagreement and discussion. Audience members will be encouraged to explore their views on conscientious objection in the same way.

Friday 23 October

Lecture by Advolly Richmond. Thomas Birch was a trained botanist, and
head gardener at Orwell Park, Ipswich, before travelling to the Gold Coast.
He became part of the international network of correspondents and plant
collectors relied upon by the Royal Botanic Gardens at Kew. This talk aims to
reveal the true extent of Birch Freeman’s horticultural and botanical legacy.
Pay at the
door: £5 (members) £8 (guests

Join Professor Chas Bountra, Professor of Translational Medicine and Professor Sir Charles Godfray as they discuss how the healthcare system has had to adapt due to the Covid-19 pandemic and what this means in the future.

How do you build inclusion from the ground up?

People with albinism face discrimination across the globe but are often left out of activist efforts around diversity and inclusion.

In this episode, we speak to representatives of Sesame Street Workshop, who have been championing diversity for years. With a breadth of expertise in the art of embracing diversity, this insightful look into the world of Sesame Street gives us new ways of approaching our goals. Supermodel and activist Diandra Forrest also joins the conversation. Fellow guest speaker Stephan Bognar, Executive Director of New York Dermatology Group Foundation, completes the line-up. They worked together previously on the Colorfull campaign, which was conceived by NYDG to highlight the prejudice that albinism attracts.

Lecture by Hanna Zembrzycka-Kisiel, Principal Major Applications Officer at
South Oxfordshire and Vale of White Horse Councils. Hanna uses the research
insights of her recent MA Thesis to explore the reality of poor urban design
and the benefits of green spaces in our living environments, drawing on local
and international urban design projects for inspiration. Book online or pay at the door.

With COVID-19 vaccines on the horizon, attention again returns to the contentious topic of whether vaccination should be made mandatory.

Recent polling has resulted in worrying headlines about a lack of willingness to have a COVID-19 vaccine if it were available.

Are mandates the answer to ensure vaccine high uptake to end the pandemic? While still a hypothetical scenario, without yet having a safe and effective vaccine approved for use, this could change in the coming months. The question of introducing mandatory vaccination spans considerations of personal liberty, health decision-making, public health and policy, as well as the relationship between the state and its citizens. Join Professor Julian Savulescu and Dr Samantha Vanderslott to debate the ethical and public policy arguments for and against mandatory COVID-19 vaccination.

Join Peter Drobac as he interviews Paul Farmer, in an exploration of the lessons we can learn from Paul Farmer’s phenomenal new book, Fevers, feuds and diamonds: Ebola and the ravages of history.

We will reflect on how these lessons can help us tackle the current Covid-19 pandemic and discuss how inequality and exploitation fuelled the spread of a deadly virus and how we might finally learn from history, in order to build a healthier, more equitable world.

For more details, visit https://www.sbs.ox.ac.uk/events/fevers-feuds-and-diamonds-dr-paul-farmer-future-global-health

Join us live or watch the recording on: https://www.sbs.ox.ac.uk/oxford-answers

This event and open to all Registration not required.

On the 30th November it was announced that the Artificial Intelligence computer programme AlphaFold had made a decisive breakthrough in the determination of the 3-D structures of proteins.

The announcement was immediately hailed as one of the major scientific advances of the decade.

Why is it important to understand the 3-D structures of protein, why are they difficult to construct, and what is the nature of AlphaFold’s advance? Why is this so exciting and what further advances in medicine and the other biosciences may result? To find out, join a conversation between Yvonne Jones, Director, Cancer Research UK Receptor Structure Research Group and Charles Godfray, Director, Oxford Martin School, who will explore these fascinating issues.

Lecture by Jane Owen, preceded by OGT’s Christmas drinks party.
Jane Owen, Founder Member of OGT, avid gardener, garden historian and
previously Deputy Editor of the Financial Times, gives us her personal take on
garden history – not to be missed! Doors open 6.30pm for wine or juice (inc), for lecture at 7pm. Book online or pay at the door.
door