As part of the Surgical Grand Round lecture series, hosted by the Nuffield Department of Surgical Sciences, Professor Chris Lavy from the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences will present ‘Public-private partnerships in elective surgery’.

Chris Powles will describe the extraordinary behaviour of elephants in Kenya’s Mount Elgon National Park, where they excavate 150m into the mountain to mine for salt.
Almost equally remarkable is the crucial role that Chris and his family have played in ensuring the survival of this unique population.

The logic and principles behind the drive for evidence-based health care are so compelling that often the limitations of evidence go unacknowledged. Despite a strong evidence base demonstrating the health risks associated with higher body weights, and health professionals routinely instructing patients to lose weight to improve their health, the incidence of obesity is predicted to continue to rise. Calling on his research into the relationships between obesity, inequality and health, Oli Williams – a fellow of The Healthcare Improvement Studies Institute – will argue that when it comes to reducing the burden on, and improving, health care a more critical approach to the way we generate, select, apply and communicate evidence is needed.

Oli Williams completed his PhD in the Department of Sociology at the University of Leicester. He was subsequently awarded the NIHR CLAHRC West Dan Hill Fellowship in Health Equity which he held at the University of Bath. He later re-joined the University of Leicester in the Department of Health Sciences working in the SAPPHIRE Group and is now based at King’s College London after being awarded a THIS Institute Postdoctoral Fellowship. His research focuses on health inequalities, the promotion of healthy lifestyles, obesity, weight stigma, equitable intervention and co-production. He co-founded the art collective Act With Love (AWL) to promote social change. The Weight of Expectation comic is one example of their work, view others at: www.actwithlove.co.uk In recognition of his work on weight stigma the British Science Association invited Oli to deliver the Margaret Mead Award Lecture for Social Sciences at the British Science Festival 2018.

This talk is being held as part of the Qualitative Research Methods course which is part of the Evidence-Based Health Care Programme. This is a free event and members of the public are welcome to attend.

Join us to learn about the progress being made in biomaterials, the next generation of innovative solutions that aim to tackle current health challenges, and what it takes to start your own venture. The event will feature talks from two prominent individuals, Dr Nick Skaer (CEO of Orthox) and Dr Nick Edwards (Co-Founder of MedInnovate and Chairman of Satie8). Dr Skaer has over 25 years’ experience in life science and materials research, and 14 years as a medtech CEO, raising over £18m. Dr Edwards has over 30 years’ experience in supporting pharmaceutical companies as ex- Global Lead of Accenture’s Pharmaceutical R&D business and current Chairman of Prescient Healthcare Group. He is a Founder of MedInnovate and an investor and supporter of life-science start-ups as well as current Chairman of Satie8.

There will be a networking & drinks reception after the event.

The event is free as always. Spots are limited, so get registered today on:

https://www.eventbrite.co.uk/e/the-next-generation-of-medical-devices-tickets-76955848013

Hella Pick is one of the trailblazers for the modern female foreign correspondent. She worked across three continents and covered the death of Yugoslavia’s leader, President Tito. Yugoslavia was always the saving grace of covering the Soviet bloc,” she remembers. “While in East Germany you were followed and listened to all the time, but Tito’s regime was a symbol of independent communism. Even the American ambassador was predicting the country would survive beyond Tito. Of course, we were all wrong.” Pick will talk about her incredible career, the stories she has covered and the current challenges facing journalism.
Neal Ascherson went to King’s College, Cambridge, where he read history. The historian Eric Hobsbawm was his tutor and described him as “perhaps the most brilliant student I ever had. I didn’t really teach him much, I just let him get on with it.” After graduating he he chose a career in journalism, first at The Manchester Guardian and then at The Scotsman, The Observer and The Independent on Sunday.He contributed scripts for the documentary series The World at War (1973–74) and the Cold War (1998). He has also been a regular contributor to the London Review of Books. Ascherson has lectured and written extensively about Polish and Eastern Europe affairs.

This is an exclusive event brought to you by the SIU in partnership with the Oxford Pharmacology Society. The application of big data and genomics in healthcare is vast, with tremendous opportunities to revolutionise current methods of diagnosing and treating diseases. Although, patient specific data is a powerful tool that can accelerate the development and translation of novel drugs and therapeutics, there are limitations to overcome. This event will take a closer look at the role of industries, academics, clinicians and healthcare policy makers in encouraging the translation of ideas into real-world solutions and the challenges within each sector. To discuss this, we will be hosting Dr Jeffrey Barrett (CSO and Director of Genomics Plc), Dr Michelle van Velthoven (Sir David Cooksey Fellow in Healthcare Translation at the University of Oxford) and Dr Amitava Banerjee (Associate Professor in Clinical Data Science at University College London).
The event will be on the 20th November at 17h30pm – 19h00, in the Department of Pharmacology. There will be a free networking & drinks reception after the event.
The event is free as always. Spots are limited, so get registered today on https://www.eventbrite.co.uk/e/pharma-and-big-data-the-healthcare-revolution-tickets-80628276345

We are entering the fourth revolution of healthcare.

The first revolution was Public Health with sanitation, cleaner air and better housing. The second is medical healthcare with the advancement of diagnostics and treatment with a focus on disease cure. The third is personalised health, through individual knowledge, technology, behaviour change and precision medicine.

However, these revolutions have left three major problems unresolved; unsustainable healthcare, rising health inequalities and climate change driven by unsustainable living.

So, we enter the fourth revolution in healthcare which builds on the previous three. This is based on communities rather than individuals, supporting a sustainable active lifestyle, eating local produce and using culture, art and contact with nature to create purpose and connections to each other, leading to greater resilience and wellbeing. It is a revolution when Smart Cities become central to the delivery of health and when advanced technology becomes almost invisible encouraging a lifestyle closer rather than further from nature.

In this talk Dr Bird will explain how we are already delivering this future and how biological changes such as chronic inflammation, epigenetics, mitochondrial dysfunction and telomere shortening can provide the scientific link between wellbeing and disease.

The talk will provide an overview of dragonflies and their life cycles and habitats as well illustrating a number of species that occur in England including those that are currently colonising from the Continent and increasing in numbers.

Tara Pirie recalls her three years living in a tent, while tracking and gathering data on these elusive, but beautiful big cats. She is now one of the world’s leading experts on Leopard ecology and conservation.

Should doctors with commercial interests lead research on their products? Should we forget ‘conflicts’ and discuss ‘declarations of interest’ instead? Who should hold and maintain conflicts of interest registers for doctors? Should practicing doctors work with the pharma industry as well as serve on guideline committees? Should researchers with extensive financial interests be disqualified from studies of their own products?

The Physician Payments Sunshine Act requires US manufacturers to collect, track and report all financial relationships with clinicians and teaching hospitals. Professor Heneghan will discuss the failings with the current system of reporting of conflicts in medicine, what’s been tried so far, and why it is time for a UK Sunshine Act.

Carl Heneghan, Professor of Evidence-Based Medicine, employs evidence-based methods to research diagnostic reasoning, test accuracy and communicating diagnostic results to a wider audience.

This talk is being held as part of the Practice of Evidence-Based Health Care module which is part of the MSc in Evidence-Based Health Care and the MSc in EBHC Systematic Reviews. Members of the public are welcome to attend.

Warburg Memorial Lecture – Joint with BBOWT
Volunteer-based botanical monitoring has been a mainstay of British and Irish botany for decades, but only recently has a recording scheme for plant communities been established. Dr Pescott outlines the history of this new National Plant Monitoring Scheme, with a particular focus on the challenges and rewards that have been associated with establishing this novel approach in the UK.

Overdiagnosis is the diagnosis of “disease” that will never cause symptoms or death during a patient’s lifetime.

Recent results of the NELSON Lung Cancer Screening Trial reports reductions in lung-cancer survival but not overall survival – The desire to detect disease even earlier means Overdiagnosis is on the rise, however, the interpretation of screening trial results is problematic and often gives rise to significant uncertainties that go unanswered.

Carl Heneghan, Professor of Evidence-Based Medicine, employs evidence-based methods to research diagnostic reasoning, test accuracy and communicating diagnostic results to a wider audience.

This talk is being held as part of the Evidence-Based Diagnosis & Screening module which is part of the MSc in Evidence-Based Health Care and the MSc in EBHC Medical Statistics. Members of the public are welcome to attend.

In this book talk, Claas will review central findings of his research on the past 80 years of antibiotic use, resistance, and regulation in food production with introduction by Prof Mark Harrison, Director of Wellcome Centre for Ethics and Humanities.

Mass-introduced after 1945, antibiotics helped revolutionise food production. Farmers and veterinarians used antibiotics to prevent and treat disease, protect plants, preserve food, and promote animals’ growth. Many soon became dependent on routine antibiotic use to sustain and increase production. The resulting growth of antibiotic infrastructures came at a price. Critics blamed antibiotics for leaving dangerous residues in food, enabling bad animal welfare, and selecting for antimicrobial resistance (AMR) in bacteria, which could no longer be treated with antibiotics.

Pyrrhic Progress analyses over 80 years of evolving non-human antibiotic use on both sides of the Atlantic and introduces readers to the historical and current complexities of antibiotic stewardship in a time of rising AMR.

This talk includes a drinks reception and nibbles, all welcome

In modern high-tech health care, patients appear to be the stumbling block.

Uninformed, anxious, noncompliant individuals with unhealthy lifestyles who demand treatments advertised by celebrities and insist on unnecessary but expensive diagnostics may eventually turn into plaintiffs. But what about their physicians? About ten years ago, Muir Gray and Gerd Gigerenzer published a book with the subtitle “Envisioning health care 2020”. They listed “seven sins” of health care systems then, one of which was health professionals’ stunning lack of risk literacy. Many were not exactly sure what a false-positive rate was, or what overdiagnosis and survival rates mean, and they were unable to evaluate articles in their own field. As a consequence, the ideals of informed consent and shared decision-making remain a pipedream – both doctors and patients are habitually misled by biased information in health brochures and advertisements. At the same time, the risk literacy problem is one of the few in health care that actually have a known solution. A quick cure is to teach efficient risk communication that fosters transparency as opposed to confusion, both in medical school and in CME. It can be done with 4th graders, so it should work with doctors, too.

Now, in 2020, can every doctor understand health statistics? In this talk, Gerd Gigerenzer will describe the efforts towards this goal, a few successes, but also the steadfast forces that undermine doctors’ ability to understand and act on evidence. Moreover, the last decade has seen two new forces that distract from solving the problem. The first is the promise of digital technology, from diagnostic AI systems to big data analytics, which consumes much of the attention. Digital technology is of little help if doctors do not understand it. Second, our efforts to make patients competent and to encourage them to articulate their values are now in conflict with the new paternalistic view that patients just need to be nudged into better behaviour.

This talk will be followed by a drinks reception, all welcome

Joint event with: The Oxford–Berlin Research Partnership

With the UK population predicted to grow nearly 20% by 2050 (circa 77 million people), over 65s making up around 25% of the population and more and more demands being put on the healthcare system what does the future hold?

Professor Chris Whitty, England’s Chief Medical Officer, will discuss predictions for the future advancement of healthcare in the UK and how these advancements will monitor, diagnose and treat us and how this will change our healthcare system.

Part of the Oxford Martin School Lecture Series: ‘Shaping the future’

We speak of earthquakes, floods, and fires as wild and untameable disasters – natural phenomena that spring unexpectedly from a hostile landscape and challenge our trust in the safety of our homes. But Ilan Kelman states otherwise. Join him as he challenges the inevitability of these disasters, suggesting that human decisions to build on flood plains, deforest territories, and impose upon the environment for social, political or economic reasons create or exacerbate these disasters. And he has some suggestions on how we can and should act to stop people suffering when nature unleashes its powers.

Ilan Kelman is Professor of Disasters and Health at University College London and a Professor at the University of Agder, Kristiansand in Norway. His overall research interest is linking disasters and health, including the integration of climate change into disaster research and health research. Suitable for ages 14+

Twitter @IlanKelman

Organised by Oxford Civic Society @oxcivicsoc. Ellie Mayhew from the Freshwater Habitats Trust will explain why our area has such rich biodiversity and what the charity has been doing to improve and monitor these valuable freshwater areas to protect the species they support.. https://www.oxcivicsoc.org.uk/programme/

Snakebite is arguably the world’s biggest hidden health crisis. It kills some 120,000 people every year, mostly from the world’s poorest communities in rural Africa, Asia and South America. The burden of death and disability is equivalent to that of prostate cancer or cervical cancer and greater than that of any other neglected tropical disease. Yet the problem is solvable – we need to bring snakebite treatment into the 21st century; we need innovative approaches to discovering and developing next generation snakebite treatments; and we need to build and importantly, sustain snakebite as a global health priority.

Dr Nick Cammack was appointed to the Wellcome Trust in September 2019 to lead an ambitious new £80 million programme aimed at driving a step-change in snakebite treatment around the world. The goal is to achieve a 50% reduction in mortality by 2030. In addition there is a pressing need to modernise the production of anti-venoms and improve their means of delivery.

Talk, followed by walking tour of the park. Jane Kilsby, local historian shares her
recent research into this well-loved 19th century public park. Maximum 20

Adults make choices regarding the technology they use to self-manage their health and wellbeing, and these technologies are often adopted, used and abused in ways that researchers, manufacturers, and clinicians have not accounted for. This talk will give an overview of human-computer interaction qualitative research on the real world use of mobile technologies in people’s everyday lives. Accounting for individual health and wellbeing choices adults make with technology, supporting choices through end user customisation, and the emerging trend towards Do-It-Yourself open-source health and wellbeing technology will be discussed. Examples of pragmatic qualitative studies will be given from research on wearables, apps, and standalone devices used for Type 1 diabetes, hearing loss, baby monitoring, and physical fitness.

Dr Aisling O’Kane is a Senior Lecturer in Human-Computer Interaction for Health and Deputy Director of the EPSRC CDT in Digital Health and Care at the University of Bristol. As a member of the Bristol Interaction Group and the Digital Health Engineering Group, she uses a pragmatic approach to qualitative research of health, wellbeing and care technologies. Dr O’Kane is currently PI of Innovate UK Machine Learning for Diabetes, co-designing AI to support diabetes self-management and Co-I of EPSRC SPHERE Next Steps, co-designing smart home technology to support health at home.

This talk is being held as part of the Advanced Qualitative Research Methods course which is part of the Evidence-Based Health Care Programme. This is a free event and members of the public are welcome to attend.

How the Freshwater Habitats Trust’s ‘Saving Oxford’s Wetland Wildlife’ project is helping to improve and monitor Oxford’s valuable freshwater areas, and protect the species they support.

In recent years there have been some alarming media stories about declines in insect populations. This talk provides an overview of trends in British insect populations over the past four decades.

To enhance our natural environment, we need to put the environment
back into the heart of the economy. Using natural capital as the
guiding principle, we can leave a better environment for future
generations, implementing a bold 25 year environment plan, thereby
restoring rivers, greening agriculture, putting nature back into towns
and cities, and restoring the uplands and our marine ecosystems. We
can put the carbon back into the soils, encourage natural carbon
sequestration, rebuild our biodiversity and improve our mental and
physical health. This is the prize – a Green and Prosperous Land – and
it is much more economically efficient than the dismal proposed of
business-as-usual and allowing the declines of the last century to
continue.

Tea/coffee, biscuits on arrival in the Committee Room. Introductory talk from Sophie Huxley, Gardener, LMH, followed by tour of the garden. Parking for 5 cars only (priority to Blue Card holders). Maximum 20 persons

Friday 23 October

Lecture by Advolly Richmond. Thomas Birch was a trained botanist, and
head gardener at Orwell Park, Ipswich, before travelling to the Gold Coast.
He became part of the international network of correspondents and plant
collectors relied upon by the Royal Botanic Gardens at Kew. This talk aims to
reveal the true extent of Birch Freeman’s horticultural and botanical legacy.
Pay at the
door: £5 (members) £8 (guests

Join Professor Chas Bountra, Professor of Translational Medicine and Professor Sir Charles Godfray as they discuss how the healthcare system has had to adapt due to the Covid-19 pandemic and what this means in the future.

The FinCEN Files investigation, coordinated by the International Consortium of Investigative Journalists, exposed more than $2 trillion in suspicious deals.

Criminals, politicians and others sent money through the world’s major banks, which initially ignored red flags or reported the money as potentially dirty after weeks, months or years of delay. Billions of dollars in suspicious deals moved from Africa into Europe, the United States, the Middle East and secretive tax havens, including payments to and from politicians and family members, state-owned oil and gas companies, arms companies and many others.

Join William Fitzgibbon and Augustin Armendariz, International Consortium of Investigative Journalists, and Taiwo Hassan Adebayo, Premium Times Nigeria, as they discuss with Professor Ricardo Soares de Oliveira what the FinCEN Files investigation has uncovered and the implications.

With COVID-19 vaccines on the horizon, attention again returns to the contentious topic of whether vaccination should be made mandatory.

Recent polling has resulted in worrying headlines about a lack of willingness to have a COVID-19 vaccine if it were available.

Are mandates the answer to ensure vaccine high uptake to end the pandemic? While still a hypothetical scenario, without yet having a safe and effective vaccine approved for use, this could change in the coming months. The question of introducing mandatory vaccination spans considerations of personal liberty, health decision-making, public health and policy, as well as the relationship between the state and its citizens. Join Professor Julian Savulescu and Dr Samantha Vanderslott to debate the ethical and public policy arguments for and against mandatory COVID-19 vaccination.

On the 30th November it was announced that the Artificial Intelligence computer programme AlphaFold had made a decisive breakthrough in the determination of the 3-D structures of proteins.

The announcement was immediately hailed as one of the major scientific advances of the decade.

Why is it important to understand the 3-D structures of protein, why are they difficult to construct, and what is the nature of AlphaFold’s advance? Why is this so exciting and what further advances in medicine and the other biosciences may result? To find out, join a conversation between Yvonne Jones, Director, Cancer Research UK Receptor Structure Research Group and Charles Godfray, Director, Oxford Martin School, who will explore these fascinating issues.

The failure to stem the tide of biodiversity loss, or to address the deeply related issue of climate change, demands we quickly find more ambitious and more coherent approaches to tackling these challenges.

Nature-based Solutions (NbS) are one such family of approaches that has recently gained prominence in international policy and business discourse. Broadly defined as actions that involve working with nature to address societal goals, NbS are being widely hailed as a win-win for addressing biodiversity loss and climate change. However, this win-win scenario is not guaranteed.

Some NbS – particularly those involving planting trees in naturally treeless habitats – can have negative outcomes for climate change mitigation, biodiversity and local peoples’ livelihoods. There are also critical questions around the timeframes over which NbS can help tackle the biodiversity and climate crises given the negative impacts of warming on the health of the biosphere.

In the second discussion in the Oxford Net Zero Series, hosted by the Oxford Martin School, Professor Nathalie Seddon, will bring together interdisciplinary researchers and practitioners to explore the value and limits of working with nature to address climate change and why NbS must both support biodiversity and be implemented with, by and for people, if they are to provide benefits over the longterm.

To register and watch this talk live: www.crowdcast.io/e/nature-climate-change

The talk will also be streamed via YouTube here: https://youtu.be/Ka7Sc5d1v3k, but please note you will not be able to take part in the interactive Q&A session unless you join the talk on CrowdCast.