The advent of super-resolution microscopy has created unprecedented opportunities to study the mammalian central nervous system, which is dominated by anatomical structures whose nanoscale dimensions critically influence their biophysical properties. I will present our recent methodological advances 1) to analyze dendritic spines in the hippocampus in vivo and 2) to visualize the extracellular space (ECS) of the brain. Using a two-photon–STED microscope equipped with a long working distance objective and ‘hippocampal window’ to reach this deeply embedded structure, we measured the density and turnover of spines on CA1 pyramidal neurons. Spine density was two times higher than reported by conventional two-photon microscopy; around 40% of all spines turned over within 4 days. A combination of 3D-STED microscopy and fluorescent labeling of the extracellular fluid allows super-resolution shadow imaging (SUSHI) of the ECS in living brain slices. SUSHI enables quantitative analyses of ECS structure and produces sharp negative images of all cellular structures, providing an unbiased view of unlabeled brain cells in live tissue.

Ada, Countess of Lovelace, is sometimes called the world’s first computer programmer. Professor Ursula Martin (University of Oxford) discusses how a young woman in the 1800s acquired the expertise to become a pioneer of computer science.
Due to popular demand this is a repeat of Professor Martin’s talk in September 2018.

Dr Imafidon, is co-founder of STEMettes, the social enterprise inspiring the next generation of females of Science, Technology, Engineering and Mathematics. One of the BBC’s 100 inspirational and innovative women for 2017.

Dr Katherine Wheelhouse did her MChem at Jesus College, Oxford, working in the chemistry department with Prof Tim Donohoe before joining GSK as a process chemist in 2008. Since 2011 Katherine has specialised in application of chemical catalysis to pharmaceutical manufacture. She is a GSK scientific fellow, a member of the RSC Applied Catalysis Committee and also of the editorial advisory board of the journal Organic Process Research and Development. Katherine is going to talk about what it is that process chemists do (to enable doing things bigger) and how this fits into the development of medicines, illustrating with some examples from recent projects.

The talk is free for OUSS members, or £2 on the door. Membership can be obtained on the night or on our website. Those interested in meeting the speaker for dinner after the talk may contact oxforduniscisoc@gmail.com. eng

Newspapers often feature studies that sound too good to be true and often they aren’t – they are myths.

Some myths may be harmless but the phenomenon affects most kinds of research within evidence-based science. The good news is that there’s a new movement tackling misleading and unreliable research and instead trying to give us results that we can trust.

Using his research in to human pheromones as an example, Tristram will discuss how and why popular myths, including power-posing, are created and how efforts have been made to address the ‘reproducibility crisis’.

Tristram Wyatt is an emeritus fellow of Kellogg College, Oxford and formerly Director of Studies in Biology at OUDCE. He is currently a Senior Research Fellow at the Department of Zoology, University of Oxford. He’s interested in how animals of all kinds use pheromones to communicate by smell. His Cambridge University Press book on pheromones and animal behaviour won the Royal Society of Biology’s prize for the Best Postgraduate Textbook in 2014. His TED talk on human pheromones has been viewed over a million times. His book Animal behaviour: A Very Short Introduction was published by Oxford University Press in 2017.

Open to all. The talk is designed for researchers from all disciplines and is open to the public.

What defines a scientific discovery with market value?

How are innovations evaluated by investors?

What makes a successful investor pitch?

How do I make personal impact?

Other than good science, it takes young entrepreneurs so much more to transfer ideas into a real business. In this event we bring in expertise from both the fundraising and the investor’s perspective, to help you address all the questions above. Join us for industry insights, chances to discuss your start-up ideas, and preparing to get your first bucket of gold!

There will be a networking & drinks reception after the event.

The event is free as always. Spots are limited, so get registered today!

Additionally, right after the event we have the chance to have formal dinner with the two guest speakers at University College for further communications. 5 spots are available and the cost of the dinner itself is payable. Message Science Innovation Union on Facebook ASAP if you are interested!

The day will consist of a range of events, hosted by speakers from different areas of STEM and industry. Expect to hear from keynote speakers, engage with panel discussions, and get hands on experience in smaller workshops focusing on entrepreneurship, outreach, disabilities and more.

Don’t miss out on hearing from a range of speakers, including: Dr. Chonnettia Jones, Director of Insight and Analysis at the Wellcome Trust; Prof. Daniela Bortoletto, Professor of Physics at Brasenose; plus Oxford’s own Vice Chancellor, Louise Richardson.

Everyone is welcome, regardless of gender, year and subject.

For more information visit OxFEST’s facebook page: https://www.facebook.com/events/294126621288050/

This is a joint lecture with The Rockefeller Foundation Economic Council on Planetary Health at the Oxford Martin School

Cooling is critical for many of the sustainable development goals, including those relating to health, shelter, livelihoods, education and nutrition. As the world’s population grows, as disposable incomes grow and as urban areas grow, the need for cooling is booming. However cooling uses super polluting gases and large amounts of energy and is therefore a significant cause of climate change. More efficient, clean cooling has the potential to avoid up to a degree of warming by the end of the century and recently all governments came together to agree action to try to maximize this opportunity. Cooling sits at the intersection of the UNFCCC, the SDGs and the Montreal Protocol, but can these forces ensure success?

Dan Hamza-Goodacre will explain the risks and possibilities in the search for sustainable cooling for all.

This talk will be followed by a drinks reception, all welcome

Currently limited tools exist to accurately forecast the complex nature of disease spread across the globe. Dr Moritz Kraemer will talk about the dynamic global maps being built, at 5km resolution, to predict the invasion of new organisms under climate change conditions and continued unplanned urbanisation.

The raw but poignant story of a mother with young onset dementia and her daughter told through dance, music and poetry. After the dance, there will be a Q&A session with artists and dementia experts including Professor Chris Kennard (University of Oxford).

Organised by Oxford Civic Society @oxcivicsoc. The ‘scientific’ study of ghosts from the 17th century onwards was followed by ‘scientific’ ghost-hunting in Victorian times. Historian Dr Allan Chapman of Wadham College lifts the lid on a fascinating application of science. What do scientists, theologians and the public think about ghosts today?. https://www.oxcivicsoc.org.uk/programme/

Talk followed by questions and discussion. All welcome

This is a joint event with the Oxford Martin School and the Oxford Climate Research Network (OCRN)

Professor David Battisti, The Tamaki Endowed Chair of Atmospheric Sciences, will be talking about global climate sensitivity controlling regional warming uncertainty and its role in impacting on human health, particularly heat stress.

As part of the NIHR Oxford Biomedical Research Centre’s Open Day, a panel of experts will discuss how artificial intelligence can be used to benefit patients and the challenges that it presents. The discussion will be chaired by Professor Lionel Tarassenko, world-leading expert in the application of signal processing to medical systems.

As part of the NIHR Oxford Biomedical Research Centre’s Open Day, Professor Ian Pavord will discuss emerging treatments for asthma, a condition that affects 5.4 million people in the UK. Professor Pavord is an internationally renowned researcher with a particular interest in asthma, chronic pulmonary disease and chronic cough.

As part of the NIHR Oxford Biomedical Research Centre’s Open Day, Dr David Eyre, an infectious diseases researcher and clinician, and Dr Katie Jeffery, Consultant in Microbiology at Oxford University Hospitals NHS Foundation Trust, will discuss how they used infection prevention and control best practice, whole genome sequencing and electronic patient data to halt an outbreak of a potentially deadly fungal pathogen at the John Radcliffe Hospital between 2015 and 2017.

The high seas are under severe pressure from both direct and indirect human impacts, including the effects of over-fishing, plastic debris and climate change. In this talk, Prof Alex Rogers will present what a network of marine protected areas in the high seas might look like, protecting 30% of known conservation features and taking into account climate change impacts. We will also hear from Dr Gwilym Rowlands, who will consider how such a network of marine protected areas could be enforced and the potential benefits to the ocean.

Aleksander Čeferin will discuss rebuilding the reputation of international football and his new four-year term plan for UEFA.

Football, the ‘beautiful game’, is the world’s most popular sport, with an estimated 4bn fans worldwide. Yet while the game is adored, how the game is governed has had a more chequered history. Two and a half years ago, a major corruption scandal at FIFA forced the resignation of Michel Platini as president of UEFA. His successor, Aleksander Čeferin, a Slovenian lawyer and moderniser, is systematically working through a plan to improve UEFA’s governance.

In this Distinguished Speaker Event, Oxford’s Rupert Younger will ask Aleksander Čeferin about his new four-year term plan for UEFA, how he is working to improve the reputation of ‘the beautiful game’, and field an open question and answer session on football and its governance.

Schedule:
17:15 – Registration opens
17:45 – Event starts
18:45 – Drinks reception (optional)
19:45 – Close

About the event
– The event is open for anyone to attend
– Please note once the main room is full you will be directed to an overflow room to watch the a livestream of the event, so please arrive early to avoid disappointment
– Spaces are limited and tickets are non-transferable, so please confirm your attendance by using the Register button above.

A storytelling lecture about how we cope with climate change from the ‘attractively impish’ (The Guardian) Dr Matt Winning. Presented by Oxford Comedy Festival.

As seen as the Environmental Correspondent on ‘Unspun with Matt Forde’ on Dave, BBC Three and BBC Radio2.

‘everything a Fringe show should be: hilarious, personal, inventive, and something that will stay with you for some time to come’ ★★★★★ (EdFestMag)

Discoveries at the frontiers of science take us into territory previously only accessed through mystical experiences.

This talk is delivered by Neville Hodgkinson.

Neville is an author and journalist. He worked for more than 30 years in UK newspapers, specialising in medicine and science. Through meditation, he learned that experiencing feelings such as love and kindness can greatly improve our physical health and wellbeing as well as helping those around us.

Astrophysics is the science of the stars, and more widely the science of the Universe. During this stellar event, Prof James Binney will present extracts from his Very Short Introduction to Astrophysics (OUP). You will learn about the rapid expansion of the field in the last century, with vast quantities of data gathered by telescopes exploiting all parts of the electromagnetic spectrum, and the great advance of computing power, which has allowed increasingly effective mathematical modelling.

The world scientific community has spent decades developing and refining magnetic confinement fusion theory and experimental devices for the ultimate goal of safely, effectively, and economically generating power from a nuclear fusion reaction.
Magnet systems are the ultimate enabling technology for these types of fusion devices. Powerful magnetic fields are required for confinement of the plasma, and, depending on the magnetic configuration, dc and/or pulsed magnetic fields are required for plasma initiation, ohmic heating, inductive current drive, plasma shaping, equilibrium, and stability control.

Almost all design concepts for power producing commercial fusion reactors rely on superconducting magnets for efficient and reliable production of these magnetic fields.

Future superconducting magnets for fusion applications require improvements in materials and components to significantly enhance the feasibility and practicality of fusion reactors as an energy source.

This lecture presents the fundamentals of superconductors and magnets that makes them attractive for use in fusion device. Examples are drawn from present operating fusion tokamak, helical, and stellarator machines that use low temperature superconductors.

I will also introduce the use of high temperature superconductors for future magnetic fusion devices, and how it may strongly influence the performance of fusion reactors.

Grab a pint and join us for a cabaret with a difference as six stellar acts take you out of this world with their entertaining riffs on life at the edge of existence. From outer space to the dinosaurs, we’ll be rocketing through a medley of music, comedy and creativity that’ll keep you weightless with laughter all night. If you love science, solar systems and stand up, this cabaret should be right up your Milky Way.

Featuring Chris Lintott (BBC Sky at Night), Lucy Rogers (Robot Wars) and many more.

This event is part of the IF Oxford Science and Ideas Festival 18-28 October 2019. IF Oxford is operating a Pay What You Decide (PWYD) ticketing system. This works by enabling you to pre-book events without paying for a ticket beforehand. Afterwards, you have the opportunity to pay what you decide you want to, or can afford. If you prefer, you can make a donation when you book.

There may be tickets available on the door – spaces may be reallocated if ticket holders are late.

IF Oxford science and ideas festival 18-28 October #IFOx2019

Join Oxford University Press for a special science-themed “speed dating” event. Mingle with a range of topics, including reptiles, psychopathy, environmental law, synaesthesia and circadian rhythms with expert authors from the Very Short Introductions series. Make an impression and get your questions in before the bell rings!

IF Oxford is operating a Pay What You Decide (PWYD) ticketing system. This works by enabling you to pre-book events without paying for a ticket beforehand. Afterwards, you have the opportunity to pay what you decide you want to, or can afford. If you prefer, you can make a donation to IF Oxford when you book. All funds raised go towards next year’s Festival.

This mesmerising and entertaining film reveals the true potential of interdisciplinary collaboration, pushing the boundaries of science storytelling. Nine scientists visit extraordinary places to uncover unexpected answers to some of humanity’s biggest questions. How did life begin? What is time? What is consciousness? How much do we really know? By introducing researchers from diverse backgrounds for the first time, this deeply human trip to the foundations of discovery reminds us that the unanswered questions are the most crucial to pose.

Pompeii Rediscovered
A talk with Massimo Osanna, Director General, Parco Archeologico di Pompei
Mon 11 Nov, 6.30–7.30pm

This event will be followed by drinks in the museum and a private view of the Last Supper in Pompeii exhibition.

In 2018, two-hundred and seventy years after excavations at Pompeii began, Director General of Pompeii, Professor Massimo Osanna, launched new excavations for conservation and research. Find out more about the amazing discoveries made in this project – from mysterious mosaics to shrines to the gods and even taverns– and learn what they reveal about daily life in Pompeii.

This event was originally scheduled for 31 October but has been moved to this new date.

Booking is essential. Tickets are £25/£22/£20 Full/Concession/Members

Join us to learn about the progress being made in biomaterials, the next generation of innovative solutions that aim to tackle current health challenges, and what it takes to start your own venture. The event will feature talks from two prominent individuals, Dr Nick Skaer (CEO of Orthox) and Dr Nick Edwards (Co-Founder of MedInnovate and Chairman of Satie8). Dr Skaer has over 25 years’ experience in life science and materials research, and 14 years as a medtech CEO, raising over £18m. Dr Edwards has over 30 years’ experience in supporting pharmaceutical companies as ex- Global Lead of Accenture’s Pharmaceutical R&D business and current Chairman of Prescient Healthcare Group. He is a Founder of MedInnovate and an investor and supporter of life-science start-ups as well as current Chairman of Satie8.

There will be a networking & drinks reception after the event.

The event is free as always. Spots are limited, so get registered today on:

https://www.eventbrite.co.uk/e/the-next-generation-of-medical-devices-tickets-76955848013

This is an exclusive event brought to you by the SIU in partnership with the Oxford Pharmacology Society. The application of big data and genomics in healthcare is vast, with tremendous opportunities to revolutionise current methods of diagnosing and treating diseases. Although, patient specific data is a powerful tool that can accelerate the development and translation of novel drugs and therapeutics, there are limitations to overcome. This event will take a closer look at the role of industries, academics, clinicians and healthcare policy makers in encouraging the translation of ideas into real-world solutions and the challenges within each sector. To discuss this, we will be hosting Dr Jeffrey Barrett (CSO and Director of Genomics Plc), Dr Michelle van Velthoven (Sir David Cooksey Fellow in Healthcare Translation at the University of Oxford) and Dr Amitava Banerjee (Associate Professor in Clinical Data Science at University College London).
The event will be on the 20th November at 17h30pm – 19h00, in the Department of Pharmacology. There will be a free networking & drinks reception after the event.
The event is free as always. Spots are limited, so get registered today on https://www.eventbrite.co.uk/e/pharma-and-big-data-the-healthcare-revolution-tickets-80628276345

This talk will describe a class of machine learning methods for reasoning about complex physical systems. The key insight is that many systems can be represented as graphs with nodes connected by edges. I’ll present a series of studies which use graph neural networks–deep neural networks that approximate functions on graphs via learned message-passing-like operations– to predict the movement of bodies in particle systems, infer hidden physical properties, control simulated robotic systems, and build physical structures. These methods are not specific to physics, however, and I’ll show how we and others have applied them to broader problem domains with rich underlying structure.