The advent of super-resolution microscopy has created unprecedented opportunities to study the mammalian central nervous system, which is dominated by anatomical structures whose nanoscale dimensions critically influence their biophysical properties. I will present our recent methodological advances 1) to analyze dendritic spines in the hippocampus in vivo and 2) to visualize the extracellular space (ECS) of the brain. Using a two-photon–STED microscope equipped with a long working distance objective and ‘hippocampal window’ to reach this deeply embedded structure, we measured the density and turnover of spines on CA1 pyramidal neurons. Spine density was two times higher than reported by conventional two-photon microscopy; around 40% of all spines turned over within 4 days. A combination of 3D-STED microscopy and fluorescent labeling of the extracellular fluid allows super-resolution shadow imaging (SUSHI) of the ECS in living brain slices. SUSHI enables quantitative analyses of ECS structure and produces sharp negative images of all cellular structures, providing an unbiased view of unlabeled brain cells in live tissue.

Warburg Memorial Lecture – Joint with BBOWT
Bryophytes in Cambridgeshire have been recorded continuously since 1927 and with increasing intensity in recent decades. A detailed analysis of the records reveals the remarkably dynamic nature of the bryophyte flora of lowland England.

‘Triboreacted materials as functional interfaces in internal combustion engines and medical implants’

Reducing CO2 and particulate emissions to halt global warming and improve the air cleanliness in developed and developing nations is urgent. A similarly large challenge is the provision of medical implants that will serve the ageing population. Both challenges are underpinned by the need to understand important functional interfaces.
This talk will focus on the engine and the hip and will present how an understanding of the interactions between tribology and chemistry/corrosion play a crucial role in the interfacial friction, wear and integrity. The integration of state-of-the-art surface science with engineering simulations in both of these areas enables engineers to create optimised systems with improved performance

Newspapers often feature studies that sound too good to be true and often they aren’t – they are myths.

Some myths may be harmless but the phenomenon affects most kinds of research within evidence-based science. The good news is that there’s a new movement tackling misleading and unreliable research and instead trying to give us results that we can trust.

Using his research in to human pheromones as an example, Tristram will discuss how and why popular myths, including power-posing, are created and how efforts have been made to address the ‘reproducibility crisis’.

Tristram Wyatt is an emeritus fellow of Kellogg College, Oxford and formerly Director of Studies in Biology at OUDCE. He is currently a Senior Research Fellow at the Department of Zoology, University of Oxford. He’s interested in how animals of all kinds use pheromones to communicate by smell. His Cambridge University Press book on pheromones and animal behaviour won the Royal Society of Biology’s prize for the Best Postgraduate Textbook in 2014. His TED talk on human pheromones has been viewed over a million times. His book Animal behaviour: A Very Short Introduction was published by Oxford University Press in 2017.

Open to all. The talk is designed for researchers from all disciplines and is open to the public.

In mammals the cell-autonomous circadian clock pivots around a transcriptional/post-translational feedback loop. However, we remain largely ignorant of the critical molecular, cell biological, and circuit-level processes that determine the precision and robustness of circadian rhythms: what keeps them on track, and what determines their period, which varies by less than 5 minutes over 24 hours? The origin of this precision and robustness is the suprachiasmatic nucleus (SCN) of the basal hypothalamus, the principal circadian pacemaker of the brain. The SCN sits atop a circadian hierarchy that sustains and synchronises the innumerable cell-autonomous clocks of all major organs to solar time (and thereby to each other), by virtue of direct retinal innervation that entrains the transcriptional oscillator of the 20,000 or so component cells of the SCN. I shall describe real-time imaging approaches to monitor circadian cycles of gene expression and cellular function in the SCN, and intersectional genetic and pharmacological explorations of the cell-autonomous and circuit-level mechanisms of circadian timekeeping. A particular focus will be on “translational switching” approaches to controlling clock function and the surprising discovery of a central role for SCN astrocytes in controlling circadian behaviour.

Talk followed by questions and discussion

All welcome

This is the latest in a series of eight weekly talks. The full list is:

Brexit: archaic techniques of ecstasy
Thursday 17 January: 7:30pm–9:00pm
Wesley Memorial Church (New Inn Hall St)

Shamanism: taking back control
Thursday 24 January: 7:30pm–9:00pm
Wesley Memorial Church (New Inn Hall St)

Tithe, timber, and the persistence of the ancien régime
Thursday 31 January: 7:30pm–9:00pm
Oxford Town Hall (St Aldates)

Hegelian dialectics and the prime numbers (part 2)
Thursday 7 February: 7:30pm–9:00pm
Wesley Memorial Church (New Inn Hall St)

Christopher Caudwell (1907–1937) and ‘the sources of poetry’
Thursday 14 February: 7:30pm–9:00pm
Wesley Memorial Church (New Inn Hall St)

Television: remote control
Thursday 21 February: 7:30pm–9:00pm
Wesley Memorial Church (New Inn Hall St)

Fascism and populism: can you spot the difference?
Thursday 28 February: 7:30pm–9:00pm
Wesley Memorial Church (New Inn Hall St)

The epos of everyday life
Thursday 7 March: 7:30pm–9:00pm
Wesley Memorial Church (New Inn Hall St)

Join us at Teddy Hall next week for a fantastic event on the ‘Neuroscience of Dance’ brought to you by the Centre for the Creative Brain!

Science, dance and wine – what more could you want for a Saturday afternoon?

A few (free) tickets are still available, so be quick!

https://www.seh.ox.ac.uk/discover/research/centre-for-the-creative-brain

Deborah Warner: Changing Directions – Journeys in theatre, opera and installation
Date: Wednesday, 27 February 2019
Time: 5.00pm (Attendees must be seated by 4.45pm)
Venue: Bernard Sunley Lecture Theatre, St Catherine’s College, Manor Road, Oxford, OX1 3UJ

Over her career, Deborah Warner has worked extensively in the fields of theatre, opera and classical music. Examples of her work as a Director include the plays Electra, King Lear and Richard II; and the operas The Turn of the Screw for the Royal Opera, which won the Evening Standard and South Bank Awards; Dido and Aeneas and La Traviata for the Vienna Festival. You can read more about Deborah Warner, and about the Cameron Mackintosh Visiting Professorship here.

Places for this event will be allocated by ballot. To register for the ballot, please complete the online form at www.stcatz.ox.ac.uk/deborahwarner by 12.00pm on Friday, 8 February. Please note that entry to the ballot does not automatically entitle applicants to a place at the lecture, but to a place in the draw. Printed confirmation of your ticket to the event will be required in order to attend the lecture.

You will be notified, via email, week commencing Monday, 18 February if you have been successful in securing a place at the lecture. Please contact development.office@stcatz.ox.ac.uk should you have any queries.

Currently limited tools exist to accurately forecast the complex nature of disease spread across the globe. Dr Moritz Kraemer will talk about the dynamic global maps being built, at 5km resolution, to predict the invasion of new organisms under climate change conditions and continued unplanned urbanisation.

ScreenTalk Oxfordshire proudly presents an evening with British Producer Jeremy Thomas. Jeremy has worked with renowned directors including Bertolucci, Nicolas Roeg, Jonathan Glazer and Ben Wheatley producing such great films as ‘The Last Emperor’, ‘Crash’, ‘Sexy Beast’ and ‘High-Rise’.

On Tuesday 5th March at the Lounge Bar, Curzon, Westgate Centre in Oxford, local producer Carl Schoenfeld will be talking to Jeremy Thomas about Directors, Actors, Crews as well as films he has produced and what he has learnt throughout his career.

Join us from 18:15 for a drink and chat in the bar, then at 19:00 with Carl Schoenfeld (ScreenTalk Co-Founder and Steering Group Member) in conversation with Jeremy Thomas (Recorded Picture Company).

There will be a Card/Cash Bar so join us after the talk to catch up and network.

ScreenTalk events are an opportunity to forge and strengthen contacts in Film, TV and Associated Media. For further information and to sign up to our mailing list please email screentalkoxfordshire@gmail.com

We expect this event to be popular and can only take pre-booked (free) tickets for entry.
Tickets: http://bit.ly/2GnlZhi

Dung beetles in the British Isles are a vital part of their associated ecosystems but have been historically rather overlooked probably due to their chosen habitat. Now our native dung beetles are finally beginning to get some of the invertebrate limelight due to an emphasis on ecosystem services and a much more environmentally friendly farming future. However we are lacking on a great deal of base data about these vitally important species and surveying is the one of the best ways to get information. This means getting into dung and discovering these unsung heroes

The ecology and history of one of the largest atolls in the world. Aldabra, situated in the South West Indian Ocean, supports the largest population of giant tortoises worldwide. A UNESCO World Heritage Site, it is a stronghold for wildlife in a region that is besieged by threats.

Professor Dave Carter reveals how understanding intercellular communication could improve healthcare.

This is a joint event with the Oxford Martin Programme on the Future of Food

Dr Mike Hamm will explore the opportunity for regional food systems in-and-around cities for mutual benefit. He will approach a number of issues – including vertical farming, bio-geochemical cycles, water use, new entry farmers, and healthy food provisioning – embedded in the notion of city region food systems with reference to supply/demand dynamics.

This talk will be followed by a drinks reception, all welcome

On Wednesday 22 May, ScreenTalk Oxfordshire proudly presents Harnessing the Power of Video in Business Communications.
An evening with Tim May, MD of Strange Films and Music, talking with Toby Low – MD of MerchantCantos an international agency specialising in bringing creativity to critical business communications; Scott Shillum – CEO of Vismedia, Winner of the 2018 Digital Impact Awards and a pioneer in creating interactive, immersive content fused with cutting edge technology; Clare Holt – Founder of Nice Tree Films in Oxford and a member of ScreenTalk provides videos for businesses, public sector organisations, charities and education; Nicky Woodhouse – Founder of Woodhouse Video Production, award-winning female director of branded content and TVCs for online and broadcast.

Join us on Wednesday 22 May from 18:15 for a drink in the downstairs Lounge Bar, Curzon, Westgate Centre in Oxford, and why not try the Curzon’s excellent Pizza – great quality! At 19:00 Tim May will be talking to Toby Low, Scott Shillum, Clare Holt and Nicky Woodhouse. Afterwards there will be Shout Outs from ScreenTalk members and facilitated networking. At ScreenTalk events we run a Card/Cash Bar so please join us and take advantage of the opportunity to catch up and network.

We expect this event to be popular and can only take pre-booked (free) tickets for entry.

Join the conversation! ScreenTalk events are an opportunity to forge and strengthen contacts in Film, TV and Associated Media.
For further information and to sign up to our mailing list please email screentalkoxfordshire@gmail.com

Content Wars: The Societal Roles and Responsibilities of Media Organisations Today
A Distinguished Speaker Seminar with Biz Stone and Dame Carolyn McCall in conversation with Dean Peter Tufano.
We are bombarded with news, information and entertainment from a growing number of content providers and technology platforms. In this hyper connected age, what are the responsibilities of leading organisations in terms of content and how it is delivered, and what trends do they believe are shaping the near future?

About the speakers

Biz Stone is best known as a technology company founder (Twitter, Medium, Jelly) and angel investor (Square, Slack, Pinterest). A progenitor of social media, Stone has been developing large scale systems that facilitate the open exchange of information for 20 years. Stone is also an author, filmmaker, philanthropist, and Visiting Fellow at Oxford University. Honors include TIME’s 100 Most Influential People in the World, The Economist’s Innovation Award, and Vanity Fair’s 2019 Global Goals List. Biz rejoined Twitter full time in 2017.

Carolyn McCall became ITV’s Chief Executive and a member of the Board of ITV in January 2018. Before joining ITV, Carolyn was the Chief Executive of Easyjet plc from 2010 to 2017 and prior to this she held several roles at the Guardian Media Group plc, including the position of Chief Executive.

Schedule

17:15 – Registration opens
17:45 – Event starts
18:45 – Drinks reception
19:45 – Close

The 5th Annual Oxford Business and Poverty Conference will feature a diverse range of speakers addressing the Paradoxes of Prosperity. Sign up here: https://www.eventbrite.com/e/5th-annual-oxford-business-poverty-conference-tickets-57733957822
Hosted at the Sheldonian Theatre, the conference will feature keynotes by:
Lant Pritchett: RISE Research Director at the Blavatnik School of Government, former Senior Fellow at the Center for Global Development
Efosa Ojomo: Global Prosperity Lead and Senior Researcher at the Clayton Christensen Institute
John Hoffmire: Director of Center on Business and Poverty and Research Associate at Kellogg Colleges at Center For Mutual and Employee-owned Business at Oxford University
Ananth Pai: Executive Director, Bharath Beedi Works Pvt. Ltd. and Director, Bharath Auto Cars Pvt
Laurel Stanfield: Assistant Professor of Marketing at Bentley College in Massachusetts
Grace Cheng: Greater China’s Country Manager for Russell Reynolds Associates
Madhusudan Jagadish: 2016 Graduate MBA, Said Business School, University of Oxford
Tentative Schedule:
2:15-2:20 Welcome
2:20-2:50 Efosa Ojomo, co-author of The Prosperity Paradox, sets the stage for the need for innovation in development
2:50-3:20 John Hoffmire, Ananth Pai and Mudhusudan Jagadish explain how the Prosperity Paradox can be used in India as a model to create good jobs for poor women
3:20-3:40 Break
3:40-4:10 Laurel Steinfeld speaks to issues of gender, development and business – addressing paradoxes related to prosperity
4:10-4:40 Grace Cheng, speaks about the history of China’s use of disruptive innovations to develop its economy
4:40-5:15 Break
5:15-6 Lant Pritchett talks on Pushing Past Poverty: Paths to Prosperity
6:30-8 Dinner at the Rhodes House – Purchase tickets after signing up for the conference
Sponsors include: Russell Reynolds, Employee Ownership Foundation, Ananth Pai Foundation and others

Our wild bees and other pollinators are so important, but they are still the unsung heroes of the environment, gardens and countryside and continue to decline in number and range. The talk will identify what we can all do to help wild bees. Many of the actions we take to protect one pollinator species, such as flower rich habitat creation and reduction in pesticide use, will assist biodiversity as a whole.

The high seas are under severe pressure from both direct and indirect human impacts, including the effects of over-fishing, plastic debris and climate change. In this talk, Prof Alex Rogers will present what a network of marine protected areas in the high seas might look like, protecting 30% of known conservation features and taking into account climate change impacts. We will also hear from Dr Gwilym Rowlands, who will consider how such a network of marine protected areas could be enforced and the potential benefits to the ocean.

It is now well-accepted that digital media platforms are not merely information intermediaries, but also central control points of the Internet. They have become the so-called ‘deciders’ and ‘custodians’ of online speech, leading to the privatization of Internet governance.

In China, domestic platforms such as WeChat, Weibo, and Toutiao have become the mediators, gatekeepers, and governors of online news and information. In order to perform this role, platforms have to work closely with the Chinese state in guiding and controlling public opinion.

The aim in this workshop is to advance analysis and understanding of the role platforms play in the governance of online news and information, and their relations with the state. After opening with a close study of the situation in China, the workshop will consider the experience of western nations, which also have to rely on private platforms to tackle issues like online hate speech, disinformation, and political or terrorism propaganda.

The workshop will gather together a number of academics working in related areas to discuss this highly topical and immensely important issue.

Presentations:
Governance regarding public opinion in a platform era: a study of China
Jufang WANG, Center for Cultural and Media Policy Studies, Warwick University

China’s control of digital infrastructure in comparative perspective
Ralph SCHROEDER, Oxford Internet Institute, Oxford University

The new governance and freedom of expression
Damian TAMBINI, Department of Media and Communications, London School of Economics

Algorithmic public sphere: controlling access to knowledge in the digital age
Roxana RADU, PCMLP/CSLS, Oxford University

Participants:
Wang Jufang, PhD candidate in Media and Communication, Warwick University, and former vice-director of news of CRI Online

Denis Galligan, Emeritus Professor of Socio-Legal Studies and Director of Programmes, Foundation for Law, Justice and Society, Oxford

Roxana Radu, Postdoctoral Researcher at the University of Oxford’s Programme in Comparative Media Law and Policy

Ralph Schroeder, Professor in Social Science of the Internet, Oxford Internet Institute, and director of its MSc programme in Social Science of the Internet

Damian Tambini, Associate Professor, Department of Media and Communications, LSE

Commentators:
Jacob Rowbottam, Associate Professor, University College, Oxford University

Pu Yan, Doctoral Student, Oxford Internet Institute, Oxford University

Dr Larkman is a retired Oxford biologist who has been chairman of OOS for the last 5 years. His main interest is the precipitous decline in the UK’s small, seed-eating farmland birds over the last 50 years.

The ability to accurately identify and interpret Track and Sign rests on a body of traditional knowledge that previous generations of naturalists would have regarded as fundamental. Sadly, now it is largely unknown and untaught, but with the upsurge of Citizen Science, it is perhaps more relevant than ever.

Slime moulds thrive in damp woodlands and normally spread over rotting logs eating bacteria and fungi. They are also unusual in being single giant cells that show remarkably sophisticated behaviour considering their humble form. This talk presents a little vignette of the science behind these curious beasts and how it has led to better understanding of other networked systems, and even the origins of civilisation.

The world scientific community has spent decades developing and refining magnetic confinement fusion theory and experimental devices for the ultimate goal of safely, effectively, and economically generating power from a nuclear fusion reaction.
Magnet systems are the ultimate enabling technology for these types of fusion devices. Powerful magnetic fields are required for confinement of the plasma, and, depending on the magnetic configuration, dc and/or pulsed magnetic fields are required for plasma initiation, ohmic heating, inductive current drive, plasma shaping, equilibrium, and stability control.

Almost all design concepts for power producing commercial fusion reactors rely on superconducting magnets for efficient and reliable production of these magnetic fields.

Future superconducting magnets for fusion applications require improvements in materials and components to significantly enhance the feasibility and practicality of fusion reactors as an energy source.

This lecture presents the fundamentals of superconductors and magnets that makes them attractive for use in fusion device. Examples are drawn from present operating fusion tokamak, helical, and stellarator machines that use low temperature superconductors.

I will also introduce the use of high temperature superconductors for future magnetic fusion devices, and how it may strongly influence the performance of fusion reactors.

Data-driven micro-targeted campaigns have become a main stable of political strategy. As personal and societal data becomes more accessible, we need to understand how it can be used and mis-used in political campaigns and whether it is relevant to regulate political candidates’ access to data.

This book talk will be followed by a drinks reception and book sale, all welcome

This is the 100 year journey to fusion: an award-winning documentary that follows the story of dedicated fusion scientists working to build a small sun on Earth, which would unleash perpetual, cheap, clean energy for mankind.
The screening will be followed by a Q&A session featuring fusion researchers.

UPP Members receive a further £2 off listed prices.

This film is rated 15.

Bernard Tucker Memorial Lecture – Joint with Oxford Ornithological Society