The advent of super-resolution microscopy has created unprecedented opportunities to study the mammalian central nervous system, which is dominated by anatomical structures whose nanoscale dimensions critically influence their biophysical properties. I will present our recent methodological advances 1) to analyze dendritic spines in the hippocampus in vivo and 2) to visualize the extracellular space (ECS) of the brain. Using a two-photon–STED microscope equipped with a long working distance objective and ‘hippocampal window’ to reach this deeply embedded structure, we measured the density and turnover of spines on CA1 pyramidal neurons. Spine density was two times higher than reported by conventional two-photon microscopy; around 40% of all spines turned over within 4 days. A combination of 3D-STED microscopy and fluorescent labeling of the extracellular fluid allows super-resolution shadow imaging (SUSHI) of the ECS in living brain slices. SUSHI enables quantitative analyses of ECS structure and produces sharp negative images of all cellular structures, providing an unbiased view of unlabeled brain cells in live tissue.

This lecture series was established in honour of our alumna, Sue Lloyd-Roberts, an award-winning broadcast journalist whose uncompromising and courageous documentaries highlighted humanitarian issues across the world.

We are delighted that our speaker this year will be world-renowned, award-winning Lyse Doucet, Chief International Correspondent and Senior Presenter for BBC World News television and BBC World Service Radio. Lyse was a BBC foreign correspondent with postings in Jerusalem, Amman, Tehran, Islamabad, Kabul and Abidjan for 15 years, before becoming a presenter in 1999. She was paramount in the coverage of the “Arab Spring” across the Middle East and North Africa and, for the past 20 years, has continued to cover all major stories in this area.

The lecture will be followed by a drinks reception. Both are free, but please register to attend. Booking deadline: 21 January.

Warburg Memorial Lecture – Joint with BBOWT
Bryophytes in Cambridgeshire have been recorded continuously since 1927 and with increasing intensity in recent decades. A detailed analysis of the records reveals the remarkably dynamic nature of the bryophyte flora of lowland England.

‘Triboreacted materials as functional interfaces in internal combustion engines and medical implants’

Reducing CO2 and particulate emissions to halt global warming and improve the air cleanliness in developed and developing nations is urgent. A similarly large challenge is the provision of medical implants that will serve the ageing population. Both challenges are underpinned by the need to understand important functional interfaces.
This talk will focus on the engine and the hip and will present how an understanding of the interactions between tribology and chemistry/corrosion play a crucial role in the interfacial friction, wear and integrity. The integration of state-of-the-art surface science with engineering simulations in both of these areas enables engineers to create optimised systems with improved performance

Newspapers often feature studies that sound too good to be true and often they aren’t – they are myths.

Some myths may be harmless but the phenomenon affects most kinds of research within evidence-based science. The good news is that there’s a new movement tackling misleading and unreliable research and instead trying to give us results that we can trust.

Using his research in to human pheromones as an example, Tristram will discuss how and why popular myths, including power-posing, are created and how efforts have been made to address the ‘reproducibility crisis’.

Tristram Wyatt is an emeritus fellow of Kellogg College, Oxford and formerly Director of Studies in Biology at OUDCE. He is currently a Senior Research Fellow at the Department of Zoology, University of Oxford. He’s interested in how animals of all kinds use pheromones to communicate by smell. His Cambridge University Press book on pheromones and animal behaviour won the Royal Society of Biology’s prize for the Best Postgraduate Textbook in 2014. His TED talk on human pheromones has been viewed over a million times. His book Animal behaviour: A Very Short Introduction was published by Oxford University Press in 2017.

Open to all. The talk is designed for researchers from all disciplines and is open to the public.

In mammals the cell-autonomous circadian clock pivots around a transcriptional/post-translational feedback loop. However, we remain largely ignorant of the critical molecular, cell biological, and circuit-level processes that determine the precision and robustness of circadian rhythms: what keeps them on track, and what determines their period, which varies by less than 5 minutes over 24 hours? The origin of this precision and robustness is the suprachiasmatic nucleus (SCN) of the basal hypothalamus, the principal circadian pacemaker of the brain. The SCN sits atop a circadian hierarchy that sustains and synchronises the innumerable cell-autonomous clocks of all major organs to solar time (and thereby to each other), by virtue of direct retinal innervation that entrains the transcriptional oscillator of the 20,000 or so component cells of the SCN. I shall describe real-time imaging approaches to monitor circadian cycles of gene expression and cellular function in the SCN, and intersectional genetic and pharmacological explorations of the cell-autonomous and circuit-level mechanisms of circadian timekeeping. A particular focus will be on “translational switching” approaches to controlling clock function and the surprising discovery of a central role for SCN astrocytes in controlling circadian behaviour.

Join 6 young people from 6 different countries to debate: ‘This House believes countries should restrict immigration to preserve national culture’ chaired and presented by the BBC’s Jonny Dymond (former BBC Correspondent Brussels, Istanbul and Washington) Book a place on eventbrite.

The day will consist of a range of events, hosted by speakers from different areas of STEM and industry. Expect to hear from keynote speakers, engage with panel discussions, and get hands on experience in smaller workshops focusing on entrepreneurship, outreach, disabilities and more.

Don’t miss out on hearing from a range of speakers, including: Dr. Chonnettia Jones, Director of Insight and Analysis at the Wellcome Trust; Prof. Daniela Bortoletto, Professor of Physics at Brasenose; plus Oxford’s own Vice Chancellor, Louise Richardson.

Everyone is welcome, regardless of gender, year and subject.

For more information visit OxFEST’s facebook page: https://www.facebook.com/events/294126621288050/

Join us at Teddy Hall next week for a fantastic event on the ‘Neuroscience of Dance’ brought to you by the Centre for the Creative Brain!

Science, dance and wine – what more could you want for a Saturday afternoon?

A few (free) tickets are still available, so be quick!

https://www.seh.ox.ac.uk/discover/research/centre-for-the-creative-brain

Brands across the UK are missing an opportunity to add up to $1bn to their brand value by failing to meaningfully reflect, represent and champion women in their marketing and advertising efforts.

In this session, we will present the findings from a research study carried out by Kantar as part of the of the What Women Want? initiative. Kantar set out to explore the concept of empowerment – what it means to women in the UK today and how brands and advertising can better connect with women. We will take a future-focused view of marketing to women discussing the Hold Her Gaze project conducted by Kantar Consulting. This work builds on the cultural conversations of today to inspire the marketing landscape of tomorrow.

You will hear from Kantar’s partners from What Women Want Steering Committee – Philippa Snare, EMEA CMO, Facebook and Justine Roberts, Founder and CEO, Mumsnet and Gransnet. In this interactive panel session, Snare and Roberts will reflect on what it takes to drive change and how it effects their brands performance, and there will be a chance for the audience to ask questions. Guided tours of the exhibition will be available both before and after the presentation.

Schedule:
18:15 – Registration opens
18:45 – Event starts
20:00 – Drinks reception (closes at 9pm)
21:00 – Close

Currently limited tools exist to accurately forecast the complex nature of disease spread across the globe. Dr Moritz Kraemer will talk about the dynamic global maps being built, at 5km resolution, to predict the invasion of new organisms under climate change conditions and continued unplanned urbanisation.

Dung beetles in the British Isles are a vital part of their associated ecosystems but have been historically rather overlooked probably due to their chosen habitat. Now our native dung beetles are finally beginning to get some of the invertebrate limelight due to an emphasis on ecosystem services and a much more environmentally friendly farming future. However we are lacking on a great deal of base data about these vitally important species and surveying is the one of the best ways to get information. This means getting into dung and discovering these unsung heroes

Organised by Oxford Civic Society @oxcivicsoc. Should we prioritise the Green Belt or new homes for Oxford? In this, the first of a series of public debates to mark the 50th anniversary of Oxford Civic Society, Bob Price, former leader of the City Council, will argue that the release of Green Belt land to meet housing need can benefit the common good without undermining the enduring purposes of the Green Belt. His view will be keenly contested by Mike Tyce, Trustee of the Campaign to Protect Rural England (CPRE) Oxfordshire. The audience will have a chance to have their say before the two opposing speakers wind up the debate.

Doors open 7.00pm; debate starts 7.30pm. Tickets required – no entry on the door.

Tickets for this event are £7 via Eventbrite – see https://www.eventbrite.co.uk/e/the-battle-for-the-green-belt-tickets-54594574843

Blackwell’s are delighted to be hosting one of Britain’s most influential literary critics, Terry Eagleton, to talk about his latest book, Humour.

A compelling guide to the fundamental place of humour and comedy within Western culture-by one of its greatest exponents

Written by an acknowledged master of comedy, this study reflects on the nature of humour and the functions it serves. Why do we laugh? What are we to make of the sheer variety of laughter, from braying and cackling to sniggering and chortling? Is humour subversive, or can it defuse dissent? Can we define wit?

Packed with illuminating ideas and a good many excellent jokes, the book critically examines various well-known theories of humour, including the idea that it springs from incongruity and the view that it reflects a mildly sadistic form of superiority to others. Drawing on a wide range of literary and philosophical sources, Terry Eagleton moves from Aristotle and Aquinas to Hobbes, Freud, and Bakhtin, looking in particular at the psychoanalytical mechanisms underlying humour and its social and political evolution over the centuries.

Jennifer Eberhardt, associate professor at Stanford University, joins us for the next in our Let’s Discuss series. She will be discussing unconscious racial bias in the context of her new book Biased. The talk will be followed by an extended time for audience Q&A so that you can really become part of the debate.

From one of the world’s leading experts on unconscious racial bias comes a landmark examination of one of the most culturally powerful issues of our time.

We might think that we treat all people equally, but we don’t. Every day, unconscious biases affect our visual perception, attention, memory and behaviour in ways that are subtle and very difficult to recognise without in-depth scientific studies.

Unconscious biases can be small and insignificant, but they affect every sector of society, leading to enormous disparities, from the classroom to the courtroom to the boardroom.

But unconscious bias is not a sin to be cured, but a universal human condition, and one that can be overcome.

In Biased, pioneering social psychologist Professor Jennifer Eberhardt explains how.

The ecology and history of one of the largest atolls in the world. Aldabra, situated in the South West Indian Ocean, supports the largest population of giant tortoises worldwide. A UNESCO World Heritage Site, it is a stronghold for wildlife in a region that is besieged by threats.

Professor Dave Carter reveals how understanding intercellular communication could improve healthcare.

Organised by Oxford Civic Society @oxcivicsoc. Council proposals to allow only electric taxis, cars, light commercial vehicles and buses to enter parts of central Oxford from 2020 proved controversial. In this second debate to mark the 50th anniversary of Oxford Civic Society, the speakers will debate when central Oxford should become a Zero Emission Zone, and what should be done about pollution in the rest of the City. How could the various ways of reducing pollution be combined and what will be the impact on people’s lives? Councillor Paul Harris, who drew attention to the problems of introducing a ZEZ very quickly, and Chris Church of Friends of the Earth, will offer their alternative proposals on 16 May. The audience will have a chance to have their say before the two opposing speakers wind up the debate.. https://www.oxcivicsoc.org.uk/programme/

This is a joint event with the Oxford Martin Programme on the Future of Food

Dr Mike Hamm will explore the opportunity for regional food systems in-and-around cities for mutual benefit. He will approach a number of issues – including vertical farming, bio-geochemical cycles, water use, new entry farmers, and healthy food provisioning – embedded in the notion of city region food systems with reference to supply/demand dynamics.

This talk will be followed by a drinks reception, all welcome

On Wednesday 22 May, ScreenTalk Oxfordshire proudly presents Harnessing the Power of Video in Business Communications.
An evening with Tim May, MD of Strange Films and Music, talking with Toby Low – MD of MerchantCantos an international agency specialising in bringing creativity to critical business communications; Scott Shillum – CEO of Vismedia, Winner of the 2018 Digital Impact Awards and a pioneer in creating interactive, immersive content fused with cutting edge technology; Clare Holt – Founder of Nice Tree Films in Oxford and a member of ScreenTalk provides videos for businesses, public sector organisations, charities and education; Nicky Woodhouse – Founder of Woodhouse Video Production, award-winning female director of branded content and TVCs for online and broadcast.

Join us on Wednesday 22 May from 18:15 for a drink in the downstairs Lounge Bar, Curzon, Westgate Centre in Oxford, and why not try the Curzon’s excellent Pizza – great quality! At 19:00 Tim May will be talking to Toby Low, Scott Shillum, Clare Holt and Nicky Woodhouse. Afterwards there will be Shout Outs from ScreenTalk members and facilitated networking. At ScreenTalk events we run a Card/Cash Bar so please join us and take advantage of the opportunity to catch up and network.

We expect this event to be popular and can only take pre-booked (free) tickets for entry.

Join the conversation! ScreenTalk events are an opportunity to forge and strengthen contacts in Film, TV and Associated Media.
For further information and to sign up to our mailing list please email screentalkoxfordshire@gmail.com

The 5th Annual Oxford Business and Poverty Conference will feature a diverse range of speakers addressing the Paradoxes of Prosperity. Sign up here: https://www.eventbrite.com/e/5th-annual-oxford-business-poverty-conference-tickets-57733957822
Hosted at the Sheldonian Theatre, the conference will feature keynotes by:
Lant Pritchett: RISE Research Director at the Blavatnik School of Government, former Senior Fellow at the Center for Global Development
Efosa Ojomo: Global Prosperity Lead and Senior Researcher at the Clayton Christensen Institute
John Hoffmire: Director of Center on Business and Poverty and Research Associate at Kellogg Colleges at Center For Mutual and Employee-owned Business at Oxford University
Ananth Pai: Executive Director, Bharath Beedi Works Pvt. Ltd. and Director, Bharath Auto Cars Pvt
Laurel Stanfield: Assistant Professor of Marketing at Bentley College in Massachusetts
Grace Cheng: Greater China’s Country Manager for Russell Reynolds Associates
Madhusudan Jagadish: 2016 Graduate MBA, Said Business School, University of Oxford
Tentative Schedule:
2:15-2:20 Welcome
2:20-2:50 Efosa Ojomo, co-author of The Prosperity Paradox, sets the stage for the need for innovation in development
2:50-3:20 John Hoffmire, Ananth Pai and Mudhusudan Jagadish explain how the Prosperity Paradox can be used in India as a model to create good jobs for poor women
3:20-3:40 Break
3:40-4:10 Laurel Steinfeld speaks to issues of gender, development and business – addressing paradoxes related to prosperity
4:10-4:40 Grace Cheng, speaks about the history of China’s use of disruptive innovations to develop its economy
4:40-5:15 Break
5:15-6 Lant Pritchett talks on Pushing Past Poverty: Paths to Prosperity
6:30-8 Dinner at the Rhodes House – Purchase tickets after signing up for the conference
Sponsors include: Russell Reynolds, Employee Ownership Foundation, Ananth Pai Foundation and others

Coriander Theatre presents a new play ‘My Mother Runs in Zig-Zags’ at the North Wall Arts Centre, 30th May – 1st June 2019, 7:30pm, Saturday Matinee 2:30pm.

Sometimes, race and trauma are like leaky old pipes: you can’t even have a friend over for dinner without something spilling out everywhere and flooding your life in the most unexpected way.

A conversation between friends becomes a journey to the Lebanese and Nigerian civil wars. Half-remembered worlds of violent oral history invade the kitchen and layer themselves over everyday life, shining light on the laughter that heals intergenerational traumas, and celebrating the overflowings and excesses of a life shaped by migration.

With an original musical score, a chorus of performance poets and contemporary dancers, and stories passed on from a generation of migrants, My mother runs in zig-zags is a bold new tragicomedy, devised by the best of Oxford University’s BAME actors and performers.

Age Guidance: 12+

My mother runs in zig zags

Our wild bees and other pollinators are so important, but they are still the unsung heroes of the environment, gardens and countryside and continue to decline in number and range. The talk will identify what we can all do to help wild bees. Many of the actions we take to protect one pollinator species, such as flower rich habitat creation and reduction in pesticide use, will assist biodiversity as a whole.

The high seas are under severe pressure from both direct and indirect human impacts, including the effects of over-fishing, plastic debris and climate change. In this talk, Prof Alex Rogers will present what a network of marine protected areas in the high seas might look like, protecting 30% of known conservation features and taking into account climate change impacts. We will also hear from Dr Gwilym Rowlands, who will consider how such a network of marine protected areas could be enforced and the potential benefits to the ocean.

Organised by Oxford Civic Society @oxcivicsoc. Government proposals for significant growth in Oxfordshire in coming decades include an Expressway and several new communities. Are these needed or can growth be directed elsewhere? Can growth be ‘intelligent’, leading to prosperity without compromising the quality of life? In the third and final debate to mark the 50th anniversary of Oxford Civic Society, Councillor Ian Hudspeth, Leader of Oxfordshire County Council, and Danny Dorling, Halford Mackinder Professor of Geography in the University of Oxford will contest the issues.. https://www.oxcivicsoc.org.uk/programme/

Dr Larkman is a retired Oxford biologist who has been chairman of OOS for the last 5 years. His main interest is the precipitous decline in the UK’s small, seed-eating farmland birds over the last 50 years.

Travis Jay presents his brand new, emotional roller-coaster of a show. It recounts Travis’s hilarious journey from childhood to fatherhood, and the many hiccups in-between.

Nominated for The Leicester Mercury Comedian of the year in 2016, Travis Jay is a stand-up, actor and radio presenter who has been performing on the comedy circuit since 2009.

Travis also writes and performs spoken word, and has featured on BBC Radio 1’s ‘First words’ poetry series alongside George The Poet. A creative, animated, and intelligent performer, Travis has built a reputation as being an entertaining and sometimes controversial story teller.

Doors at 5.30pm/Show at 6pm